https://www.jrnls.org/ijnp New articles published in Indian Journal of Natural Products. en Wed, 01 Jan 2025 00:00:00 GMT https://www.jrnls.org/ijnp/37/1/1 https://www.jrnls.org/ijnp/37/1/1 Wed, 01 Jan 2025 00:00:00 GMT V.K. Dixit Indian Journal of Natural Products The Indian Journal of Natural Products is committed for publishing high-quality, scientifically rigorous, and impactful research that advances knowledge in the field of natural products and related areas. Maintaining these standards is central to the journal’s mission and to serving our authors, reviewers and the readership. We wish to inform our contributors and readers that there has been a delay in the publication schedule of the journal. The primary reason for this delay has been a paucity… https://www.jrnls.org/ijnp/37/1/2 https://www.jrnls.org/ijnp/37/1/2 Wed, 01 Jan 2025 00:00:00 GMT Sukhdev Chandel, Neeraj Agrawal, Lowkesh Chandravanshi, Satyawati Rathia, Chandan Kumar Sahu, Arun Kumar Singh Parihar, Umesh Kumar Patil, Nagendra Singh Chauhan Indian Journal of Natural Products Amalaki avaleha an ayurvedic formulation that highlights the Rasayana and blood enhancing properties of Amalaki. Amalaki Avaleha is mentioned in Sushruta samhita Uttar Tantra in reference of Pandu roga (Anemia). This study is based on the HPTLC analysis of two active Phytochemicals constituents’ Gallic acid and Ascorbic acid present in Amalaki avaleha to authenticate its phytochemical profile and substantiate its therapeutic claims. Pre-coated silica gel 60 F254 plates used for evaluation.… https://www.jrnls.org/ijnp/37/1/12 https://www.jrnls.org/ijnp/37/1/12 Wed, 01 Jan 2025 00:00:00 GMT Aditi Gupta, Harshita Singhai, Devyani Rajput, Umesh Kumar Patil Indian Journal of Natural Products Millets are traditionally known for their high nutritional values, climate resilience, and ability to grow even in harsh environment. They have been significantly cultivated as sustainable crops for their need of low water requirement, tolerance to drought like conditions, and adaptability to marginal lands. They significantly help in dealing global problems of food insecurity, climate change, and malnourishment. Further, their rich nutritional value, including dietary fiber, protein content,… https://www.jrnls.org/ijnp/37/1/22 https://www.jrnls.org/ijnp/37/1/22 Wed, 01 Jan 2025 00:00:00 GMT Saurav Kumar, Rohan Pradhan, Gajendra Singh, Sagar Sagar Indian Journal of Natural Products Its excellent medical potential and widespread demand for its herbal products have led to indiscriminate exploitation and a severe risk of extinction. A durable and effective method has been created for both seed and semi-hard stem cutting propagation. Certain growth hormones have been applied at varying concentrations. At 10 mg/L (96.67%), catchin acid had the highest sprouting percentage, whereas tanic acid had the lowest at 2.5 mg/L (24.0%). In the second year, IBA 250 mg/L (85.33%)… https://www.jrnls.org/ijnp/37/1/30 https://www.jrnls.org/ijnp/37/1/30 Wed, 01 Jan 2025 00:00:00 GMT Elias Mjaika Ndifon Indian Journal of Natural Products The assessment of Indigenous edible insects is crucial because they represent a powerful solution to food security and protein deficiency. Their exceptional potential as nutritious food sources, animal feed, and health-enhancing products must be acknowledged to effectively tackle food insecurity in underserved regions. Embracing these insects is not just beneficial; it is essential for a sustainable future. Questionnaires were administered in 11 towns/villages in six out of 13 Local Government… https://www.jrnls.org/ijnp/37/1/39 https://www.jrnls.org/ijnp/37/1/39 Wed, 01 Jan 2025 00:00:00 GMT Karishma Khobragade, Prakash Itankar, Satyendra Prasad, Suhas Dhaswadikar, Satish Meshram, Anil Badnale, Yogesh Nikam Indian Journal of Natural Products The current study aimed to standardize a commercial formulation of Sidh Tulsi oil and its constituent oils of various Ocimum species, including Ocimum sanctum, Ocimum basillicum, Ocimum gratissimum, Ocimum canum, and Ocimum citriodorum. After evaluating the physicochemical, pharmaceutical parameters, and the phytochemical study found that marketed formulations and their oils contained significant amounts of secondary metabolites, primarily polyphenols, flavonoids, tannins, triterpenoids,… https://www.jrnls.org/ijnp/36/1/2 https://www.jrnls.org/ijnp/36/1/2 Sat, 01 Jan 2022 00:00:00 GMT Disha Sharma, Vandana Singh, Manoj Kumar Yadav, Umesh Kumar Patil, Vinod Kumar Dixit, Narayan Prasad Yadav Indian Journal of Natural Products Mosquitoes are majorly responsible for causing vector-borne diseases such as malaria, filariasis, chikungunya, dengue, zika, yellow fever, west nile etc. Aedes, Anopheles, Culex are the main genera among other mosquitoes’ species, that are affecting human beings with such dreadful diseases worldwide. To control the transmission of diseases by mosquitoes generally mosquito nets, ITNs and LLINs, DDT, DEET, IR3535 are being used. Prolong use of these harmful chemicals not only cause development of… https://www.jrnls.org/ijnp/36/1/17 https://www.jrnls.org/ijnp/36/1/17 Sat, 01 Jan 2022 00:00:00 GMT Leena R Dhoble, Prakash R Itankar Indian Journal of Natural Products Aim: Our research work deals with chromatographic standardisation of the ‘smart crop’ mungbean or Phaseolus radiatus L. Wilczek using high performance liquid chromatography (HPLC) with respect to vitexin, in addition to pharmacognostic and phytochemical analysis.Materials and Methods: Pharmacognostic standardisation of the plant included macroscopy, powder microscopy, physicochemical parameters, preliminary phytochemical screening, heavy metal testing and microbial contamination studies.… https://www.jrnls.org/ijnp/36/1/24 https://www.jrnls.org/ijnp/36/1/24 Sat, 01 Jan 2022 00:00:00 GMT Ravichand Meshram, Umakant Sahu, Arun K S Parihar, Prashant K Gupta, Nagendra Singh Chauhan Indian Journal of Natural Products The aim of this study was to find out a simple, accurate and sensitive HPTLC method for the detection and quantification of marker molecule Gallic and Piperine in Padmakadi churna for standardization. Ethanolic extraction was performed for analysis. HPTLC was done using gallic acid and Piperine as a standard. The mobile phase was a mixture of Toulene:ethyl acetate:Ethanol:Formic acid (6:3:1:0.3 v/v/v) and detection at 254 nm. The Rf was detected at - 0.39 for Gallic acid and Rf - 0.55 for… https://www.jrnls.org/ijnp/36/1/28 https://www.jrnls.org/ijnp/36/1/28 Sat, 01 Jan 2022 00:00:00 GMT Alok Nahata, Vinod Kumar Dixit Indian Journal of Natural Products Ganoderma lucidum is considered to be a natural medicine that promotes longevity and maintains the vitality of human beings. Its beneficial clinical effects in patients with hepatitis, hyperglycemia, chronic bronchitis, cancer, muscular dystrophy, arteriosclerosis, hypertension, hypercholesterolemia, and leukopenia have been confirmed in pharmacologic studies in recent years. The fruiting bodies, mycelia, and spores have recently received more and more attention not only as home remedies but… https://www.jrnls.org/ijnp/36/1/39 https://www.jrnls.org/ijnp/36/1/39 Sat, 01 Jan 2022 00:00:00 GMT Ch. Raja Shekar, Ajmera Rama Rao, Umesh K Patil, Ciddi Veeresham Indian Journal of Natural Products The biotransformation reaction of cell suspension cultures produced from Decalepis hamiltonii and Nicotiana tabacum leaves were investigated, using Carvedilol drug. Interestingly, the cell suspension cultures showed biotransformation of racemic carvedilol. There is noticeable conversion of S-enantiomer to R-enantiomer of Carvedilol. The bio-conversion was detected and quantified by Chiral HPLC. The ideal biotransformation was achieved with the concentration of 0.1mg/ml Carvedilol at pH 5.8. The… https://www.jrnls.org/ijnp/36/1/44 https://www.jrnls.org/ijnp/36/1/44 Sat, 01 Jan 2022 00:00:00 GMT Swati Srivastava, Divya Rani Sharma, Arvind Kumar Srivastava, Alok Mukerjee, Abhishek Kumar Tripathi, Sunil Kumar Singh Indian Journal of Natural Products Background: Wounds are a serious worldwide health problem that place significant economic, financial, and social strain on health care organizations, professionals, patients, and their families.Aim: To investigate the anti- inflammatory and wound healing activity of ethanolic extract of leaves Cycas revoluta.Materials and Methods: In albino rats, the anti- inflammatory and wound healing activity was explored using complete excision, incision wound model and paw edema induced wound model. The… https://www.jrnls.org/ijnp/36/1/52 https://www.jrnls.org/ijnp/36/1/52 Sat, 01 Jan 2022 00:00:00 GMT Rajesh Singh Pawar, Avinash Singh Mandloi, Umesh Kumar Patil, Shweta Kumar Indian Journal of Natural Products Introduction: This work is focus on a cost-effective herbal hydrogel formulation comprising of extract, from the leaves of Cassia occidentalis L. (Caesalpiniaceae). The formulation is highly effective for delayed wound healing due to diabetes.Background: Cassia occidentalis (CO) is extensively used in folklore medicine system. It is a common weed scattered from foothills of Himalayas to West Bengal, South India, Burma and Srilanka.Objectives: The study aimed to explore the role of Cassia… https://www.jrnls.org/ijnp/35/1/1 https://www.jrnls.org/ijnp/35/1/1 Fri, 01 Jan 2021 00:00:00 GMT Vinod Kumar Dixit Indian Journal of Natural Products I am happy to present this issue of Indian Journal of Natural Products (IJNP) after a considerably long period of time. The unprecedented delay was primarily because of Covid-19 pandemic and the desire of the executive council members and other office bearers to project it on international platform and also because of the paucity of quality papers/article benefitting and addressing the current science of natural products. It is our endeavour to publish the journal through internationally… https://www.jrnls.org/ijnp/35/1/2 https://www.jrnls.org/ijnp/35/1/2 Fri, 01 Jan 2021 00:00:00 GMT Preet Amol Singh, Neha Bajwa, Ashish Baldi Indian Journal of Natural Products The world economy of the international trade of herbs and related products has been witnessing an increase of 15% annually. In the aftermath of the COVID-19 outbreak, there are reports highlighting an instant rise in the demand for medicinal plants especially the immunity booster plants. Due to the anti-oxidant, anti-inflammatory, anti-viral, anti-bacterial and antifungal properties of Curcuma longa L. popularly known as Turmeric and Haldi in India, herbal scientists are exploring this… https://www.jrnls.org/ijnp/35/1/9 https://www.jrnls.org/ijnp/35/1/9 Fri, 01 Jan 2021 00:00:00 GMT Vikas Sharma, Nagendra S Chauhan, Umesh K Patil, Vinod Kumar Dixit Indian Journal of Natural Products In recent years, the use of the herbs in reducing heavy metal toxicities has increased worldwide. Rasayana drugs have been reported to have improved reproductive activity. In this study, we investigated the protective effects of Anacyclus pyrethrum, Spilanthes acmella and Pedalium murex on lead acetate-induced testicular damage in rats. The sample used 30 male rats divided into 5 groups: negative control (rats were given daily with 1% sodium CMC solution were given daily with lead acetate in… https://www.jrnls.org/ijnp/35/1/16 https://www.jrnls.org/ijnp/35/1/16 Fri, 01 Jan 2021 00:00:00 GMT Sanjay Mishra, Damita Cota, Sunil Satyappa Jalalpure Indian Journal of Natural Products Background: Quercetin is known for its vast pharmacological activities in recent years. It has shown beneficial effects in animal models of colitis. Purpose: The effectiveness of quercetin in human IBD is limited. Results from these pre-clinical studies indicate an opportunity for developing anti-colitic polyphenol treatments.Methods: In the present study. Quercetin was evaluated for its antimicrobial potential against clinical isolates of IBD patients (HM95, HM233, HM251, HM615). Cytotoxicity… https://www.jrnls.org/ijnp/35/1/19 https://www.jrnls.org/ijnp/35/1/19 Fri, 01 Jan 2021 00:00:00 GMT Neeraj Kumar Shrivastava, Alok Mukerjee, Sunil Kumar Singh, Abhishek Kumar Tripathi, Arvind Kumar Srivastava Indian Journal of Natural Products Present study includes the ameliorating effect of dried extract seed of Prunus dulcis (Mill.) D.A. Webb var. amara (DC.) on Scopolamine hydrobromide (ScHBr) induced memory impairment in rats, cholinesterase activity and oxidative stress. Cognitive disorders include various factors as amnesia, difficulties in attention and Alzheimer’s disease (AD) and other neurologically disorders. Basic mechanism of neuro related disorder underlies with neuroapoptsis. The term Neuroapoptsis means dead of… https://www.jrnls.org/ijnp/35/1/25 https://www.jrnls.org/ijnp/35/1/25 Fri, 01 Jan 2021 00:00:00 GMT Sagar Soundalgekar, Atish Naik, Kirankumar Hullatti, Sunil Jalalpure, Sneha Patil, Vishakha Parab Gaonkar Indian Journal of Natural Products The present research work aims at developing HPTLC fingerprints of two sources of Bharangi Clerodendrum serratum (Linn.) and Clerodendrum indicum (Linn.), along with in vivo antiasthmatic evaluation in OVA-induced Wistar rat model. Air dried roots of both plants were subjected for extraction by maceration followed by soxhlet using ethanol (80%). Further a HPTLC fingerprints was developed for the quantification of Oleanolic acid and Stigma sterol to distinguish both the plants. The… https://www.jrnls.org/ijnp/35/1/32 https://www.jrnls.org/ijnp/35/1/32 Fri, 01 Jan 2021 00:00:00 GMT Renuka Mahajan, Prakash Itankar Indian Journal of Natural Products Aim: The study aims screening of phytochemicals and standardization of extract of Pedalium murex Linn. fruits.Methods: The extraction was carried out by maceration technique using 70% ethanol and 30% water. The aqueous ethanolic extract obtained was estimated for total phenolic and flavonoid content against the standard gallic acid and quercetin. Liquid –liquid partitioning method using solvents n-hexane, chloroform, ethylacetate provided the different fractions of aqueous ethanolic extract.… https://www.jrnls.org/ijnp/35/1/38 https://www.jrnls.org/ijnp/35/1/38 Fri, 01 Jan 2021 00:00:00 GMT Shubham Sharma, Ranjit Singh Kushwaha, Subh Naman, Umesh Kumar Patil, Ashish Baldi Indian Journal of Natural Products Background: Capsaicin, the main active constituent of oleoresin capsicum present in capsicum fruits, is responsible for their pungency and color. Capsaicinoids is an important phytoconstituents and hence exported for various benefits. Hypothesis of work: The process of extraction of oleoresin capsicum by reflux method was to be optimized using in terms of their percentage yield. Further ICH complicent analytical method for quantitative analysis of caipsaicin using HPLC was developed and… https://www.jrnls.org/ijnp/33/1/2 https://www.jrnls.org/ijnp/33/1/2 Tue, 01 Jan 2019 00:00:00 GMT Chanchal Garg, Munish Garg Indian Journal of Natural Products Photoaging is a multifactorial process which is attributed mainly to the degree of sun exposure and the amount of melanin present in the skin. The elemental root of skin aging is the generation of free radicals i.e. reactive oxygen species (ROS) and the oxidative stress. This oxidative stress highly affects the skin as it is rich in lipids, proteins, carbohydrates, DNA etc. Although, it has been well demonstrated that the skin has its own exceptionally effective natural antioxidant defence… https://www.jrnls.org/ijnp/33/1/18 https://www.jrnls.org/ijnp/33/1/18 Tue, 01 Jan 2019 00:00:00 GMT Yamjala Ganeshkumar, Perala Kavitha, Ajmera Ramarao, Ciddi Veeresham* Indian Journal of Natural Products Background: Andrographis paniculata (Burm. F.) Wall ex. Nees, belonging to the family Acanthaceae produces a group of diterpene lactones, one of which is the pharmaceutically important andrographolide. Hypothesis:It is known to possess various important biological properties like hepatoptroective, anticancer, anti-HIV, anti inflammatory, etc. Method:The production of andrographolide in the cell suspension cultures of Andrographis paniculata by elicitation was investigated. Results: Arachidonic… https://www.jrnls.org/ijnp/33/1/24 https://www.jrnls.org/ijnp/33/1/24 Tue, 01 Jan 2019 00:00:00 GMT Vikas Sharma, Nagendra S. Chauhan, U. K. Patil, V.K. Dixit Indian Journal of Natural Products Background: According to Indian Systems of Medicine, Spilanthes acmella (L.)Murr.Anacyclus pyrethrum DC, Pedalium murex Linn.is considered effective in the treatment of sexual deficiencies especially due to aging. Purpose:To assess the effect of ethanolic extracts of theAnacyclus pyrethrum roots, Spilanthes acmella flowers and Pedalium murex fruits in sexual behavior of old age rats Method:In the present study ethanolic extracts of theAnacyclus pyrethrum roots, Spilanthes acmella flowers and… https://www.jrnls.org/ijnp/33/1/30 https://www.jrnls.org/ijnp/33/1/30 Tue, 01 Jan 2019 00:00:00 GMT Malleswara Rao Peram, Sunil S Jalalpure, Sumit A Joshi Indian Journal of Natural Products Background: Curcumin derived from the dried rhizomes of turmeric has been extensively studied due to its wide range of biological activities and pharmacological effects. Previously reported HPLC methods have several disadvantages such as long run time, high flow rate, higher limits of detection and quantification, complicated mobile phase compositions with gradient elution and very low pH conditions. Purpose:To develop a simple, rapid, economic, precise and accurate reverse phase high… https://www.jrnls.org/ijnp/33/1/35 https://www.jrnls.org/ijnp/33/1/35 Tue, 01 Jan 2019 00:00:00 GMT Nidhi Jasani, Nagja Tripathi, Vimal Kumar Indian Journal of Natural Products Background: Lagenaria siceraria Mol. Standley commonly known as bottle gourd is a climbing perennial herb cultivated as a vegetable in the tropical countries. Lagenaria siceraria leaves are used traditionally for cough, bronchitis, asthma and inflammation.Purpose: On basis of ethano-medicinal uses, the anti-allergic activities of the methanolic extract of Lagenaria siceraria leaves was planned to investigate scientifically using animal models for allergic inflammation and anti-allergic… https://www.jrnls.org/ijnp/33/1/39 https://www.jrnls.org/ijnp/33/1/39 Tue, 01 Jan 2019 00:00:00 GMT Tiewlasubon Uriah, Mrityunjaya Patil, Sivaiah Kummara Indian Journal of Natural Products Aim: To evaluate the in vitro antioxidant and hepatoprotective activity of Potentilla fulgensroot extracts against ethanol-induced hepatotoxicity. Materials and methods:In vitro antioxidant activity for the methanolic and aqueous root extracts of Potentilla fulgens was carried out by DPPH, superoxide anion and hydroxyl radical scavenging methods. For hepatoprotective effect, the hepatic markers such as alanine aminotransferase (ALT), aspartate amino transferase (AST), alkaline phosphatase… https://www.jrnls.org/ijnp/33/1/49 https://www.jrnls.org/ijnp/33/1/49 Tue, 01 Jan 2019 00:00:00 GMT Karuna P. Modi, Kashmir B. Pagi, Suman K. Lahiri, Mamta B. Shah Indian Journal of Natural Products Background: Ipomoea turpethum R. Br.(F: Convolvulaceae)commonly known as Indian Jalap in English and Nisoth in Hindi has been commonly used as a purgative. In India under the name of Nisoth two drugs are available commercially, Marsdeniatenacissima as white Nisoth and Ipomoea turpethum as black Nisoth. The presence of a coumarin, scopoletin in I. turpethum distinguishes the two drugs available under the name of Nisoth. Purpose: This paper is aimed to present a simple method of identification… https://www.jrnls.org/ijnp/33/1/53 https://www.jrnls.org/ijnp/33/1/53 Tue, 01 Jan 2019 00:00:00 GMT Tarkeshwar Dubey, Kancharla Bhanukiran, Siva Hemalatha Indian Journal of Natural Products Background: Blumea lacera (Burm.f.) DC.(Asteraceae) is one of the annual herb indigenous to plains of North-west India, Tropical Africa and South East Asia. Hypothesis:Despite the popular exploitation of this herb as medicine, still no proper study has been reported regarding the pharmacognostical standardization of its leaves. Thus, the aim of the present study was to scientifically establish a standard monograph based on pharmacognostical and phytochemical aspects as per World Health… https://www.jrnls.org/ijnp/33/1/60 https://www.jrnls.org/ijnp/33/1/60 Tue, 01 Jan 2019 00:00:00 GMT Sawale J A, Kori M L, Patel J R Indian Journal of Natural Products Background:Euphorbia neriifolia leaves belonging to family euphorbiaceae being used traditionally for the treatment of asthma, bronchitis, tumours, leucoderma, piles, inflammations and ulcers. Earlier studies reported various chemical constituents such as euphorbon, resin, euphorbol and euphol. Hypothesis of work: On the basis of recent studies, it is concluded that reactive oxygen species are involved in several diseases. Hence the present study investigated to isolate the compounds from…