https://www.jrnls.org/jppcm New articles published in Journal of Pharmacy Practice and Community Medicine. en Fri, 01 Jan 2027 00:00:00 GMT https://www.jrnls.org/jppcm/13/1/1 https://www.jrnls.org/jppcm/13/1/1 Fri, 01 Jan 2027 00:00:00 GMT Kavita Namdev, Malay Choudhary, Mahendra Kumar Tamrakar, Lavesh Vyas, Lavish Verma, Kuldeep Vishwakarma Journal of Pharmacy Practice and Community Medicine Healthcare systems over the world are facing a lot of pressure. This is because there are many patients and not enough healthcare professionals. Also, some people do not have access to medical advice when they need it. The MediBot is a computer program that uses intelligence to talk to people about their medical symptoms. People can tell MediBot what is wrong with them in their words. Then MediBot tries to figure out what might be wrong. Suggests some over-thecounter medicines that people can… https://www.jrnls.org/jppcm/13/1/10 https://www.jrnls.org/jppcm/13/1/10 Mon, 01 Mar 2027 00:00:00 GMT Aftab Hussain Journal of Pharmacy Practice and Community Medicine India bears the highest global burden of Tuberculosis (TB), accounting for nearly one-quarter of worldwide cases, with persistent challenges related to Multidrug-Resistant TB (MDR-TB) and healthcare access. In alignment with the WHO End TB Strategy, India committed to eliminating TB by 2025, five years ahead of the global Sustainable Development Goals target. The National TB Elimination Program (NTEP), evolved from the Revised National Tuberculosis Control Programme (RNTCP), serves as the… https://www.jrnls.org/jppcm/13/1/18 https://www.jrnls.org/jppcm/13/1/18 Fri, 01 Jan 2027 00:00:00 GMT Sri Bhagya Sarojini Devi Dondapati, B. Vijay Kumar, D. Rama Brahma Reddy Journal of Pharmacy Practice and Community Medicine Alzheimer's Disease (AD) is a progressive neurodegenerative disorder characterized by amyloid-β plaques and tau neurofibrillary tangles, necessitating early and accurate diagnosis for effective intervention. Recent advances in Artificial Intelligence (AI) have significantly enhanced the discovery and interpretation of AD biomarkers by enabling the integration of complex, multimodal datasets, including neuroimaging, molecular, genetic, and digital biomarkers. AI-driven approaches, particularly… https://www.jrnls.org/jppcm/13/1/24 https://www.jrnls.org/jppcm/13/1/24 Mon, 01 Mar 2027 00:00:00 GMT Aftab Hussain Journal of Pharmacy Practice and Community Medicine Cardiovascular Diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Their management requires long-term, multi-drug therapy, which increases the risk of Adverse Drug Reactions (ADRs) in patients. The objective of this systematic review was to summarize the pattern, severity, and drug-class distribution of ADRs associated with cardiovascular drugs, using published studies alongside FAERS and PvPI pharmacovigilance data. The review was conducted following PRISMA guidelines.… https://www.jrnls.org/jppcm/13/1/32 https://www.jrnls.org/jppcm/13/1/32 Fri, 01 Jan 2027 00:00:00 GMT Pragatheesh N, Nandana S, Sriram S, Sam Johnson Udaya Chander J Journal of Pharmacy Practice and Community Medicine Surgery is increasingly recognized as a complex, longitudinal therapeutic process spanning preoperative preparation, anesthesia, intraoperative care, and postoperative recovery rather than an isolated operating room event. Because this continuum is highly medication-intensive and subject to challenges like polypharmacy, rapid drug administration, physiological instability, multiple transitions of care, and communication failures, the perioperative environment carries a high risk for preventable… https://www.jrnls.org/jppcm/13/1/42 https://www.jrnls.org/jppcm/13/1/42 Mon, 01 Mar 2027 00:00:00 GMT Nitika Sharma, Sonika Rattan, Atul Sharma, S Sharad Journal of Pharmacy Practice and Community Medicine Quality Control (QC) and Quality Assurance (QA) are key elements in the pharmaceutical sector. They help to ensure the safety, efficacy and consistency of medicines. This article discusses the purpose of QC and QA for pharmaceutical manufacturing in the modern era and outlines their development, principles and problems relating to the application of technology and universal quality standards. The article reaffirms the need for continuous and seamless improvement in the maintenance of quality… https://www.jrnls.org/jppcm/13/1/50 https://www.jrnls.org/jppcm/13/1/50 Mon, 01 Mar 2027 00:00:00 GMT H. S. Shekar, Syed Raziuddin Faisal, B. Nagaraju Journal of Pharmacy Practice and Community Medicine Background: Type 2 Diabetes Mellitus (T2DM) is a Pathobiologically complex metabolic disorder characterized by chronic hyperglycemia, progressive β-cell failure, and systemic insulin resistance, precipitating microvascular and macrovascular sequelae, with persistent metabolic disequilibrium driven by therapeutic inertia, adherence attrition, and inadequacies in structured, patient-centric care paradigms. Objectives: To systematically delineate the longitudinal efficacy of a protocol-driven,… https://www.jrnls.org/jppcm/13/1/60 https://www.jrnls.org/jppcm/13/1/60 Fri, 01 Jan 2027 00:00:00 GMT Pravartika Gandhi, Ranveer Sahrawat, Preeta Kaur Chugh Journal of Pharmacy Practice and Community Medicine Background: Serious Adverse Drug Reactions (sADRs) are one of the important causes of morbidity and mortality. In India, pharmacovigilance practices are evolving but comprehensive regional data on sADRs is lacking. Understanding how sADR prevalence in India compares with global patterns is essential to improve patient safety. Aims and Objectives: This study aimed to compare the prevalence of selected sADRs associated with commonly used drugs in India and other countries, and to examine the… https://www.jrnls.org/jppcm/13/1/65 https://www.jrnls.org/jppcm/13/1/65 Mon, 01 Mar 2027 00:00:00 GMT Dudhat Himani Rameshbhai, Yadav Khushi Umeshbhai, Patel Payal Rajeshbhai, Dabhi Sherin Sandeepkumar, Palak Kandarp Vyas Journal of Pharmacy Practice and Community Medicine Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder among women of reproductive age. It is marked by hormonal imbalance, ovulatory dysfunction, and metabolic irregularities, which can contribute to infertility and long-term health risks. Objectives: This study aimed to evaluate the clinical features and treatment practices in patients diagnosed with PCOS. Materials and Methods: A retrospective observational analysis was carried out using medical records of 65 PCOS… https://www.jrnls.org/jppcm/13/1/74 https://www.jrnls.org/jppcm/13/1/74 Fri, 01 Jan 2027 00:00:00 GMT Darshan Tm, Banjara Raju Prabhudev, Balakeshwa Ramaiah Journal of Pharmacy Practice and Community Medicine Background: Chronic Kidney Disease (CKD) significantly alters drug pharmacokinetics, increasing the risk of drug accumulation, toxicity, and adverse drug reactions. The coexistence of multiple comorbidities frequently leads to polypharmacy, necessitating careful dose individualization. Objectives: To evaluate prescribing patterns, drug utilization, and renal dose adjustment practices in patients with CKD in a tertiary care setting. Materials and Methods: A prospective observational study was… https://www.jrnls.org/jppcm/13/1/82 https://www.jrnls.org/jppcm/13/1/82 Fri, 01 Jan 2027 00:00:00 GMT Sankaralingam Ramalakshmi, Suriya Prakash Mani, Thamizhselvan Ravi, Mohammed Arshad Zahir, Varshnee Ezhilan, Akshaya Gopinathan Journal of Pharmacy Practice and Community Medicine Background: Pharmacovigilance plays a vital role in ensuring medication safety through the detection, assessment, understanding, and prevention of Adverse Drug Reactions (ADRs), with community pharmacists serving as key contributors to ADR reporting. Objectives: To assess the Knowledge, Attitude, and Practice (KAP) regarding ADR reporting among community pharmacists. Materials and Methods: A prospective observational study was conducted among 75 community pharmacists over a period of 2 months… https://www.jrnls.org/jppcm/13/1/89 https://www.jrnls.org/jppcm/13/1/89 Mon, 01 Mar 2027 00:00:00 GMT Vemula Jyothi, Sudarsanam Mounika, Kethireddy Pradeep, Kolapalli Prasanthi, Shaik Faizan Ali Journal of Pharmacy Practice and Community Medicine Background: Cancer treatment often imposes a substantial financial burden on patients, commonly described as financial toxicity. This financial burden and the complexity of anticancer medications may increase the risk of Drug-Related Problems (DRPs) and negatively affect the patient's Quality of Life (QoL). Improving patient-centered oncology care requires evaluating these factors. Objectives: The purpose of this study was to use standardized assessment tools to evaluate financial toxicity,… https://www.jrnls.org/jppcm/13/1/101 https://www.jrnls.org/jppcm/13/1/101 Mon, 01 Mar 2027 00:00:00 GMT Ankit Paradkar, Praveen Khirwadkar Journal of Pharmacy Practice and Community Medicine Background/Objectives: This study assessed operational, financial and technology-adoption challenges among retail pharmacies in Ujjain, Madhya Pradesh, and used the findings to design a context-appropriate AI-driven smart pharmacy framework. Materials and Methods: A cross-sectional descriptive survey with mixed-methods instrumentation was conducted among 56 retail pharmacies across four geographic zones of Ujjain using a 26-item questionnaire. Quantitative responses were analysed using… https://www.jrnls.org/jppcm/13/1/110 https://www.jrnls.org/jppcm/13/1/110 Fri, 01 Jan 2027 00:00:00 GMT Supalash Das, Balakeshwa Ramaiah Journal of Pharmacy Practice and Community Medicine Lithium is an effective mood stabilizer with a narrow therapeutic window and is primarily cleared by the kidneys. Conditions such as acute illness, fluid volume depletion, disturbances in sodium levels, and concurrent drug use can elevate the risk of lithium-induced neurotoxicity. A 57-year-old man with bipolar disorder, type 2 diabetes, hypertension, and ischemic heart disease was admitted due to vomiting, reduced oral intake, and diabetic ketoacidosis. He had been taking lithium carbonate 400… https://www.jrnls.org/jppcm/13/1/113 https://www.jrnls.org/jppcm/13/1/113 Fri, 01 Jan 2027 00:00:00 GMT Niranjan Giri, Umesh Maske, Kailas Rathod, Quadri Sohel Journal of Pharmacy Practice and Community Medicine The development of pharmaceutical formulations is changing. It is moving away from trial-anderror ways. Now modern approaches rely on science and data. Quality by Design or QbD offers a structured way to develop medicines. It starts with defining the Quality Target Product Profile or QTPP. Then it identifies Critical Quality Attributes or CQAs. It also looks at Critical Material Attributes or CMAs and Critical Process Parameters or CPPs. Design of Experiments or DoE helps in planning studies.… https://www.jrnls.org/jppcm/13/1/120 https://www.jrnls.org/jppcm/13/1/120 Mon, 01 Mar 2027 00:00:00 GMT Niranjan Giri Journal of Pharmacy Practice and Community Medicine Aim and objectives: The aim of this study was to develop a robust manufacturing process for gelatin-based nutraceutical gummies using a Quality by Design (QbD) approach. The objectives were to identify the Critical Process Parameters (CPPs) that influence the Critical Quality Attributes (CQAs) of the gummies, to optimism these parameters, and to establish a design space and control strategy for consistent production. Materials and Methods: The Quality Target Product Profile and CQAs were… https://www.jrnls.org/jppcm/12/4/202 https://www.jrnls.org/jppcm/12/4/202 Tue, 14 Jul 2026 00:00:00 GMT Rajkumari Lodhi, Virendra Kumar Sharma Journal of Pharmacy Practice and Community Medicine Alzheimer’s disease is the leading cause of dementia and represents the most prevalent neurodegenerative condition worldwide. It is characterized by progressive deterioration in short-term memory and cognitive abilities, eventually interfering with everyday activities and behavior. Although most cases occur sporadically, a smaller proportion is inherited, enabling the identification of specific genes that, along with neuropathological findings, provide valuable insight into the broader origins… https://www.jrnls.org/jppcm/12/4/211 https://www.jrnls.org/jppcm/12/4/211 Tue, 14 Jul 2026 00:00:00 GMT Abdul Manaf Fathima Zanooja* Journal of Pharmacy Practice and Community Medicine Four-Dimensional (4D) printing is transforming pharmaceutical manufacturing by enabling the development of adaptive drug delivery systems capable of responding dynamically to physiological and environmental stimuli. Among the most promising innovations in this field are 4D printed stimuli-responsive polypills, which integrate multiple active pharmaceutical ingredients within a single programmable dosage form capable of controlled and personalized drug release. These systems utilize smart… https://www.jrnls.org/jppcm/12/4/217 https://www.jrnls.org/jppcm/12/4/217 Tue, 14 Jul 2026 00:00:00 GMT Pooja Chandrasekar, Mariyam Susan Joji, Sashtipriyaa Ramesh, Jagadeesan Moorthy Journal of Pharmacy Practice and Community Medicine According to the World Health Organisation, the Defined Daily Dose is the estimated daily maintenance dosage for a medication used for its primary indication in humans. Drug dose determination is extremely important for any drug. When a newly created, more precise dose plan differs considerably from the authorised label, it is crucial to assess the stage of proof needed to modify the label and clinical practice. Age has a significant influence on dose modification, as the acronym implies,… https://www.jrnls.org/jppcm/12/4/228 https://www.jrnls.org/jppcm/12/4/228 Tue, 14 Jul 2026 00:00:00 GMT Dharva Shah* Journal of Pharmacy Practice and Community Medicine Artificial Intelligence (AI) is rapidly transforming the pharmaceutical industry through its integration into pharmacovigilance, drug discovery, predictive analytics, and healthcare governance systems. Traditional pharmacovigilance frameworks rely heavily on spontaneous reporting systems and manual signal detection processes, resulting in delayed identification of adverse drug reactions, fragmented healthcare datasets, and under-reporting. AI-driven technologies such as Machine Learning (ML),… https://www.jrnls.org/jppcm/12/4/234 https://www.jrnls.org/jppcm/12/4/234 Tue, 14 Jul 2026 00:00:00 GMT Saicharan Madagoni, Siri Chandana Eeda, Priyanka Machavaram, Sana Firdouse, Anoosha Bera Journal of Pharmacy Practice and Community Medicine Aim: The main aim is to assess the factors concerning medication non-adherence and uncontrolled seizures. Materials and Methods: This is a hospital-based prospective observational study conducted in the outpatient department over 6 months, with patients who met the inclusion criteria. Patient’s medication beliefs were assessed using the Beliefs about Medicines Questionnaire [BMQ]. The level of adherence was calculated using Morisky’s Medication Adherence Scale [MMAS-8] to identify factors… https://www.jrnls.org/jppcm/12/4/242 https://www.jrnls.org/jppcm/12/4/242 Tue, 14 Jul 2026 00:00:00 GMT Khaled Al-Akhali, Abdullah Mahyuob, Yousef Al-Ghobabi Journal of Pharmacy Practice and Community Medicine Background: Hypertension remains a leading cause of cardiovascular morbidity in low resource settings, yet data on real-world management practices in conflict-affected regions such as Yemen remain scarce. Aim: To evaluate demographic characteristics, adherence to non-pharmacologic therapy, and antihypertensive prescribing patterns among hypertensive patients attending AL-Thawra Hospital, Sana'a City, Yemen. Materials and Methods: A hospital-based, cross-sectional study was conducted among 120… https://www.jrnls.org/jppcm/12/4/248 https://www.jrnls.org/jppcm/12/4/248 Tue, 14 Jul 2026 00:00:00 GMT Monday Ikponmwosa Osarenmwinda, John Nonso Eze Journal of Pharmacy Practice and Community Medicine Background: Understanding cost and other barriers to Pharmaceutical Care Services (PCS) delivery in Nigeria is key to improving practice and informed government resource allocation. Objectives: This study identifies barriers, perceived value of, and willingness to pay for PCS at University of Benin Teaching Hospital UBTH, Benin City. Materials and Methods: A cross-sectional study was conducted among 311 patients who visited the General Practice Clinic (GPC) pharmacy unit of UBTH. Data were… https://www.jrnls.org/jppcm/12/4/257 https://www.jrnls.org/jppcm/12/4/257 Thu, 01 Jan 2026 00:00:00 GMT Saicharan Madagoni* Journal of Pharmacy Practice and Community Medicine Background: Vitamin D deficiency is a pervasive public health concern in India, with reported prevalence rates of 70-90%. Emerging evidence suggests a relationship between hypovitaminosis D and psychiatric morbidity; however, comprehensive data examining multiple mental health domains simultaneously in the Indian context remain sparse. Objectives: To evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and depression, anxiety, perceived stress, sleep disturbance, fatigue,… https://www.jrnls.org/jppcm/12/4/268 https://www.jrnls.org/jppcm/12/4/268 Tue, 14 Jul 2026 00:00:00 GMT Simran Khanam, Saman Moin, Rajesh Yadav Journal of Pharmacy Practice and Community Medicine Objectives: The present study was conducted to assess the Knowledge, Attitude, and Practice (KAP) regarding the use of Over-the-Counter (OTC) drugs among 101 participants. Materials and Methods: A cross-sectional survey was carried out using a structured questionnaire. Participants. The majority of participants belonged to the 21-23 years age group (38.6%), with a mean age of 21.84 years. Results: The results showed that 83.2% of participants reported using OTC medicines, with most using them… https://www.jrnls.org/jppcm/12/4/276 https://www.jrnls.org/jppcm/12/4/276 Tue, 14 Jul 2026 00:00:00 GMT Sourabh Bhardwaj, Devarati Majumdar, Venkatesan Nalliah Journal of Pharmacy Practice and Community Medicine Introduction: The Centralized Clinical Pharmacy model in multi-branch hospitals plays a pivotal role in enhancing patient safety by minimizing medication errors through the standardization of prescription review and documentation. Objectives: To evaluate the effectiveness of the centralized pharmacist oversight in identifying and correcting prescribing issues. Materials and Methods: A review of 17,255 prescription checks was conducted to assess the prevalence of medication errors. Results: The… https://www.jrnls.org/jppcm/12/4/284 https://www.jrnls.org/jppcm/12/4/284 Tue, 14 Jul 2026 00:00:00 GMT Sumedh Sanjay Joshi* Journal of Pharmacy Practice and Community Medicine Diabetes mellitus is a chronic disease that leads to persistent high blood sugar along with dysfunction of various metabolic systems. Though effective, the latest drug therapies still have some problems like causing side effects and not being able to stop the progression of the loss of cell mass. To study the anti-diabetic potential of Sphaeranthus indicus Linn., a plant that is highly valued in Ayurvedic medicine, this research employs a computational framework linking network pharmacology,… https://www.jrnls.org/jppcm/12/4/295 https://www.jrnls.org/jppcm/12/4/295 Tue, 14 Jul 2026 00:00:00 GMT Saicharan Madagoni* Journal of Pharmacy Practice and Community Medicine Background: Vitamin D deficiency is a pervasive public health concern in India, with reported prevalence rates of 70-90%. Emerging evidence suggests a relationship between hypovitaminosis D and psychiatric morbidity; however, comprehensive data examining multiple mental health domains simultaneously in the Indian context remain sparse. Objectives: To evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and depression, anxiety, perceived stress, sleep disturbance, fatigue,… https://www.jrnls.org/jppcm/12/4/305 https://www.jrnls.org/jppcm/12/4/305 Tue, 14 Jul 2026 00:00:00 GMT V. Aiswarya, Sermuga Pandian Nithya, E.D Giridar Priyan, Manikandan V Journal of Pharmacy Practice and Community Medicine Background: Helminth infections continue to be a major public health and the veterinary problem, especially in the tropical and subtropical regions. In recent years, the resistance is commonly used anthelmintic drugs has increased which has reduced their therapeutic effectiveness. Because there is a need to explore alternative sources of antiparasitic agents. Medicinal plants that contain a wide range of secondary metabolites and considered a promising source for the development of new… https://www.jrnls.org/jppcm/12/4/312 https://www.jrnls.org/jppcm/12/4/312 Tue, 14 Jul 2026 00:00:00 GMT Maha Abdul-Latif, Nadin Suleiman, Victoria Wright, Jorge Sanchez Journal of Pharmacy Practice and Community Medicine Demonstrate a specific vancomycin regimen for patients with hyper-glomerular filtration rate that was used in clinical practice achieving the therapeutic Area Under the Curve (AUC) without nephrotoxicity incidence. 2020 guidelines recommend using the area under the curve to estimate vancomycin therapeutic concentration rather than using trough due to lower nephrotoxicity risk. However, there is insufficient evidence of the optimized vancomycin dose in patients with augmented renal clearance. In…