https://www.jrnls.org/phres New articles published in Pharmacognosy Research. en Wed, 01 Dec 2027 00:00:00 GMT https://www.jrnls.org/phres/19/1/1 https://www.jrnls.org/phres/19/1/1 Wed, 01 Dec 2027 00:00:00 GMT Sivaranajani Balakrishnan, Karthikeyan Ramadoss, Geetha Govindarajulu Pharmacognosy Research The current review summarizes the processes, characteristics and uses of Nanoparticles (NPs) sourced from polyherbal formulations, such as fullerenes, metal NPs, ceramic NPs and polymeric NPs. In order to make different and useful nanoparticles from polyherbal combinations the medicinal values of several plants have to be animals. These nanoparticles have unique properties, such as improved stability, controlled-release, and targeted delivery methods, which make them considerable assets for… https://www.jrnls.org/phres/19/1/10 https://www.jrnls.org/phres/19/1/10 Wed, 01 Dec 2027 00:00:00 GMT Sivasubramanian Piramanayagam, Sakthi Puvisha Muthu, Elango Gopalan, Cibi Veeramani, Shalini Balraj, Ragavi Sivakumar, Pushparam Asaithambi Pharmacognosy Research Pithecellobium dulce (Roxb.) Benth is a medicinal plant that is commonly used in traditional medicine and its phytochemical profile has shown to contain numerous bioactive compounds which are characterized by the presence of high concentration of flavonoids (42-57 mg QE/g), phenolics (30-75 mg GAE/g), tannins, alkaloids, saponins, sterols and terpenoids. These ingredients together contribute to the wide phytochemical properties. Quantitative tests showed strong antioxidant activity (DPPH… https://www.jrnls.org/phres/19/1/21 https://www.jrnls.org/phres/19/1/21 Wed, 01 Dec 2027 00:00:00 GMT Divya Kanojiya, Suzain Garasiya, Ghanshyam Parmar Pharmacognosy Research Neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and Autism lead to Central Nervous System (CNS) degeneration, impairing both cognitive and motor functions. With the rising prevalence of these illnesses-closely linked to age and lifestyle factors-effective therapeutic strategies that can cross the Blood-Brain Barrier (BBB) is urgently needed. Conventional medications often fail due to the restrictive nature of the BBB, which has prompted growing interest in… https://www.jrnls.org/phres/19/1/34 https://www.jrnls.org/phres/19/1/34 Mon, 01 Mar 2027 00:00:00 GMT Hanan Bahjat Khojah Pharmacognosy Research Plant byproducts have been used as supplements owing to their antimicrobial, antioxidant, and anti-inflammatory properties. They also help treat and prevent many dental problems. However, the use of herbal treatments presents challenges for researchers. This narrative review highlights the evidence of the most clinically useful natural products in dental care published in Q1 to Q4 journals from 2010 to 2026. A comprehensive literature survey was performed using the Google Scholar and PubMed… https://www.jrnls.org/phres/19/1/40 https://www.jrnls.org/phres/19/1/40 Tue, 01 Dec 2026 00:00:00 GMT Swetasri Priyadarshini, Sabir Kumar Behera, Mukunda Ghadai, A Leelaveni Pharmacognosy Research Background: The traditional understanding of plant-based medicine has been passed down through the ages and has been assimilated by various ethnic groups as ethnopharmacological knowledge. The present study focuses on the specific phytochemical makeup, therapeutic applications, and pharmacological characteristics of the various components of this multifunctional tree, Z. oenoplia, collected from tribal areas of the Badangi region in Ganjam district, Odisha. Ziziphus oenoplia (L.) Mill., known… https://www.jrnls.org/phres/19/1/49 https://www.jrnls.org/phres/19/1/49 Tue, 01 Dec 2026 00:00:00 GMT Ankita Haldankar, Niraj Vyawahare, Pavankumar Wankhade, Shubhangi Daswadkar, Kaveri Urade Pharmacognosy Research Background: Bronchial Asthma (BA) is a chronic inflammatory airway disorder strongly associated with immune system dysregulation. Daidzein, a natural isoflavone found in soy, exhibits well-documented anti-inflammatory and immunomodulatory activities, including inhibition of dendritic cell maturation and regulation of effector cell functions. Objectives: To investigate the anti-asthmatic potential of Daidzein through diverse in vitro and in vivo experimental models, including an Ovalbumin… https://www.jrnls.org/phres/19/1/65 https://www.jrnls.org/phres/19/1/65 Wed, 01 Dec 2027 00:00:00 GMT Swarnabha Mukherjee, Neha Mondal, Shreya Mondal, Gargi Banerjee, Tushar Adhikari Pharmacognosy Research Background: Unripe fruits are promising sources of nutrition in the daily diet, which have gained attention for their rich phytochemical profile and associated health benefits. Objectives: The present study aimed to profile the phytochemical constituents of unripe fruits of Ficus carica and Phyllanthus emblica grown in West Bengal and to evaluate their in vitro antidiabetic and anti-inflammatory potential. Materials and Methods: Quantitative estimation of Total Flavonoid Content (TFC), Total… https://www.jrnls.org/phres/19/1/72 https://www.jrnls.org/phres/19/1/72 Tue, 01 Dec 2026 00:00:00 GMT Sachin Baburao Mulik, Sanjay Uttamrao Nipanikar, Priyanka Patil, Ankita Kasabe, Pravin Surwade Pharmacognosy Research Background: High Performance Thin Layer Chromatography (HPTLC) is an advanced analytical technique used for the identification and quantification of marker compounds in Ayurvedic formulations. Aims and Objectives: The purpose of this study is to create and validate an HPTLC method for the simultaneous estimation and quantification of four marker compounds: Vasicine (VS), Gallic Acid (GA), Piperine (PP), and Pterostilbene (PTS) from two formulations: Amarantha Gynorite syrup and Amarantha… https://www.jrnls.org/phres/19/1/86 https://www.jrnls.org/phres/19/1/86 Tue, 01 Dec 2026 00:00:00 GMT Ramanjaneyulu Kanugala, Goli Penchala Pratap, Mohd Kashif Husain, Maramreddy Prathapa Reddy, Sidama Gopal, Mohammad Zakir, Gudivada Sudarsanam Pharmacognosy Research Background: Elaeodendron glaucum (Rottb.) Pers. is an essential ethnomedicinal plant belonging to Celastraceae used in the treatment of various ailments like antidotes for snake bites, dog bites, wounds and cracks, dysuria, swellings, burning sensations, hyperacidity, dysentery, headaches, fever, etc. Aim: The Present study aimed to establish the pharmacognostical profile of Elaeodendron glaucum to generate data on distinguishing characteristics from other Elaeodendron species. Materials and… https://www.jrnls.org/phres/19/1/100 https://www.jrnls.org/phres/19/1/100 Tue, 01 Dec 2026 00:00:00 GMT Neha Suresh Palase, Santosh Y Mudakappagol Pharmacognosy Research Background: The scientific validation of traditional as well as proprietary Ayurvedic formulations is crucial for the purpose of healing of wound in chronic non healing wounds. Polyherbal Formulation Extracted Ointment, a proprietary formulation made up of Water-soluble extracts of Nirgundi patra, Amalaki Bark and Bhringraja whole plant with simple ointment base. All three drugs are having Wound healing activity which mentioned in ayurveda classical texts as Vranaropana, Vrana-shodhana,… https://www.jrnls.org/phres/19/1/116 https://www.jrnls.org/phres/19/1/116 Wed, 01 Dec 2027 00:00:00 GMT Amitha Mohan, Anoop Kumar, Abilasha Ramasubramanian Pharmacognosy Research Introduction: Oral Squamous Cell Carcinoma (OSCC) continues to be a significant global health challenge, especially in developing areas, where lifestyle associated risk factors increase its prevalence. Even with improvements in surgery, radiotherapy, and chemoradiation, toxicities related to treatment and resistance still undermine clinical outcomes, driving the quest for safer, plant-derived supplements. The Tephrosia genus, characterised by a rich content of rotenoids, flavonoids, and… https://www.jrnls.org/phres/19/1/124 https://www.jrnls.org/phres/19/1/124 Mon, 01 Mar 2027 00:00:00 GMT Sushmita Sanjay Gengane, Anil Koralli, Pranjali Abhay Patil, Shreya Balasaheb Nikam Pharmacognosy Research Background: Shatapushpadi Lepa is a traditional external application specified in Ayurveda. The composition that is advised for Vata-dominant inflammatory joint diseases. To determine quality, and therapeutic effectiveness, such a conventional formulation must be scientifically validated. Purpose: The present study is aimed to evaluate the quality of shatapushpadi lepa in inflammatory joint diseases like Rheumatoid arthritis through physiochemical, phytochemical profiling and Chromatographic… https://www.jrnls.org/phres/19/1/133 https://www.jrnls.org/phres/19/1/133 Sun, 01 Mar 2026 00:00:00 GMT Sabira Nissar, Tahir Mushtaq, P. A. Sofi, Ishtiyak Ahmad Peerzada, Meraj U Din Dar, A. R. Malik, Ummar Atta, Moamenla Jamir Pharmacognosy Research Background: The Kashmir Himalaya is known for its rich diversity of medicinal plants that support traditional healthcare systems, where indigenous knowledge plays a vital role in disease management. Among these, Bergenia ciliata is widely recognized for its therapeutic potential; however, comprehensive studies integrating its morphology, ethnobotanical importance and formulation development are limited. Materials and Methods: The present study aimed to document the morphological… https://www.jrnls.org/phres/19/1/141 https://www.jrnls.org/phres/19/1/141 Sun, 01 Mar 2026 00:00:00 GMT Preethi Vem, Sathwika Rao Nadipelli, Daneswari Velagala, Vaishnavi Julakanti, Shivani Thoom, Deekshita Kavali Venugopal, Naseemoon Shaik Pharmacognosy Research Background: Maintenance of asepsis is essential for successful endodontic therapy. Gutta-percha cones are susceptible to microbial contamination during handling and storage, and their thermoplastic nature precludes heat sterilization, making rapid chemical disinfection necessary. Purpose: This study evaluated the comparative antimicrobial activity of chemical and herbal agents used for rapid gutta-percha cone decontamination against E. faecalis. Materials and Methods: This in vitro experimental… https://www.jrnls.org/phres/19/1/146 https://www.jrnls.org/phres/19/1/146 Sun, 01 Mar 2026 00:00:00 GMT Shreya Balasaheb Nikam, Rajashekhar Sanapeti, Anil Koralli, Shubham Deepak Anuse, Sushmita Sanjay Gengane Pharmacognosy Research Background: Dashmoola Kashaya is ayurvedic polyherbal formulation prepared from roots of ten medicinal plants which are traditionally used in the management of disorders like inflammatory conditions, neuromuscular disorders, respiratory diseases and musculoskeletal pain. To validate the quality and pharmacological relevance, scientific evaluation using modern technique is essential. Purpose: This study of Gas Chromatography-Mass Spectrometry (GC-MS) analysis to examine the Dashmoola Kashaya,… https://www.jrnls.org/phres/19/1/154 https://www.jrnls.org/phres/19/1/154 Sun, 01 Mar 2026 00:00:00 GMT Pravin Kadappa Koparde, Mujahid Khan, Sheetal Pravin Koparde Pharmacognosy Research Background: Traditional Ayurvedic Herbal remedies have long been used to improve and revitalize reproductive health. Siddha Shalmali Kalpa (Classical Shalmali malabarica formulation) is one such formulation that has long been praised for its aphrodisiac qualities. Its safety profile is still not well supported by scientific research, nevertheless. Purpose: In order to lay the groundwork for next pharmacological and clinical studies, this study sought to assess the acute oral toxicity of Siddha… https://www.jrnls.org/phres/19/1/162 https://www.jrnls.org/phres/19/1/162 Sun, 01 Mar 2026 00:00:00 GMT Dagvadorj Tserendorj, Javkhlan Bold, Myagmardash Bazarragchaa, Darmaa Munkhdorj, Bayar Enkhbold, Bold Sharav Pharmacognosy Research Background: Ancient Mongolian doctors and scholar-monks identified diseases that were prevalent among Mongolians but were not described in Indian Ayurveda or Tibetan medicine. Based on the theory of wind, bile, and phlegm, they revised the classification of diseases to incorporate these conditions. A notable example is the entirely new systematization of the classification, nomenclature, diagnosis, and treatment of infectious diseases. Consequently, attention must be directed to the works of… https://www.jrnls.org/phres/19/1/168 https://www.jrnls.org/phres/19/1/168 Sun, 01 Mar 2026 00:00:00 GMT KJ Sharmila, Nishalini Palani, Aarthy Sundaram, Santhiya Jayakumar Pharmacognosy Research Background: Tinospora cordifolia is used worldwide for its medicinal properties, but its bioactive phytoconstituents have been less explored. Objectives: The fresh and dry leaf extracts of Tinospora cordifolia, a traditional medicinal plant, were comparatively analysed for their phytochemical content and therapeutic potential. Materials and Methods: Qualitative methods such as Fourier Transform Infra-Red spectroscopy (FTIR), Gas Chromatography-Mass Spectrometry (GCMS), antimicrobial assay and… https://www.jrnls.org/phres/19/1/176 https://www.jrnls.org/phres/19/1/176 Sun, 01 Mar 2026 00:00:00 GMT Vani Manjappa Karadi, Manjula Mavathuru Venkatappa, Shivakumar Venkataramaiah, Sanjana Bai Shivaram Singh Mahendaranath Singh, Sushma Mohan, Ramesh Komalapura Lakshmaiah, Devaraja Sannaningaiah Pharmacognosy Research Background: In recent years, the prevalence of diabetes has increased dramatically worldwide. Although several drugs are available for its management, their severe cytotoxic effects have created a need for safer and more effective alternatives. Urolithins (A, B, C, D, M5, M6, and M7) have gained attention due to their pharmacological potential; however, Urolithin-C remains the least studied. In our previous study, we reported the anti-inflammatory mechanism of chemically synthesized… https://www.jrnls.org/phres/19/1/185 https://www.jrnls.org/phres/19/1/185 Sun, 01 Mar 2026 00:00:00 GMT Vandana Tyagi, Namita Arora, Pankaj Arora Pharmacognosy Research Background: Atherosclerotic Cardiovascular Disease (ASCVD) is largely caused by hyperlipidemia, characterized by high cholesterol and triglyceride levels. Standard treatments like statins face limitations such as intolerance and poor adherence. This study uses amalgamated in silico techniques to screen and identify potential lipid-lowering phytoconstituents from traditional medicinal herbs to develop safe polyherbal formulations. Materials and Methods: A multi-tiered virtual screening narrowed… https://www.jrnls.org/phres/19/1/202 https://www.jrnls.org/phres/19/1/202 Sun, 01 Mar 2026 00:00:00 GMT Sanyogeeta Ajay Dixit, Pankaj Sharma, Pradnya Prakash Hemke, Kashavva Veerabasayya Hiremath, Susmita Devgonda Shedbale, Namrata Bhagaje, Monika Yadav Pharmacognosy Research Background: Non-Specific Hairfall (NSHF), classified as Khalitya in Ayurveda (NAMC FA-3, ICD-11 TM2), has a significant global burden. Kaidarya siddha Narikela Taila (KNT) is a formulation prepared with Narikela Taila (Cocos nucifera) and Kaidarya kashaya (decoction of Murraya koenigii), widely utilised in the management of Khalitya. Aim and Objectives: To identify and analyse the phytochemical profile of Kaidarya siddha Narikela Taila (KNT) by Gas Chromatography-Mass Spectrometry (GC-MS) and… https://www.jrnls.org/phres/19/1/215 https://www.jrnls.org/phres/19/1/215 Sun, 01 Mar 2026 00:00:00 GMT Jinavani Jeevagan, Shaira Banu Ismail, Abarna Balasubramani, Priyadharshini Muniyasamy, Murugesan Sannasi, Sathish Adithya, Rajathinakaran, Madhavan Ramachandran Pharmacognosy Research Background: Alcoholic Liver Disease (ALD) is a major cause of cirrhosis-related morbidity and mortality, with limited therapies. Alcohol Dehydrogenase (ADH) plays a key role in ethanol metabolism and contributes to hepatic injury. Siddha formulations are rich in bioactive phytoconstituents with potential hepatoprotective effects. Objectives: To evaluate the drug-likeness and inhibitory potential of bioactive phytoconstituents from Thaalisaathi Chooranam against Human Alcohol Dehydrogenase using… https://www.jrnls.org/phres/19/1/224 https://www.jrnls.org/phres/19/1/224 Sun, 01 Mar 2026 00:00:00 GMT Priya Darshani Koul, Yadevendra Yadav, Shuchi Mitra, Khemchand Sharma Pharmacognosy Research Background: Shoolaharana Yoga, described in Rasendra Sara Saṃgraha, is a classical Herbo-mineral formulation indicated for various types of pain. Ayurvedic pharmaceutical processes such as Shodhana (Purification) and Bhavana (Trituration) are traditionally employed to enhance safety, bioavailability, and therapeutic potential. In the present era, integration of classical processing with modern extraction techniques warrants systematic analytical evaluation. Objectives: The present study aimed… https://www.jrnls.org/phres/19/1/233 https://www.jrnls.org/phres/19/1/233 Sun, 01 Mar 2026 00:00:00 GMT Rashmi Shahi, Suvarna V. Chavannavar, N Bharath Kumar, M.S Yashaswini Pharmacognosy Research Background: Nigella sativa, also referred as black cumin and described as the miraculous herb, exhibits many medicinal and pharmacological properties. Objectives: This research focused on the antimicrobial effectiveness of different N. sativa Seeds (NSS) extracts against spoilage microbes and phytochemical analysis of seed extract via Gas Chromatography-Mass Spectrometry (GC-MS). Materials and Methods: Using agar well diffusion method, acetone, hexane, ethanolic and aqueous extracts of N.… https://www.jrnls.org/phres/19/1/243 https://www.jrnls.org/phres/19/1/243 Sun, 01 Mar 2026 00:00:00 GMT Saranya Ramsridhar, R Chandini, Vishnupriya Veeraraghavan, Khadijah Mohideen, Mutaz Ali-Hassan, Murali Balasubramaniam Pharmacognosy Research Background: Oral Squamous Cell Carcinoma (OSCC) remains a major global health challenge despite advances in conventional therapies. Growing interest in Complementary and Alternative Medicine (CAM) has heightened attention to natural and plant-based therapies such as Thuja occidentalis (T. occidentalis) in oral cancer management. Healthcare professionals play an important role in guiding evidence-based use of these therapies. Objectives: To evaluate the Knowledge, Attitudes, and Practices (KAP)… https://www.jrnls.org/phres/19/1/252 https://www.jrnls.org/phres/19/1/252 Sun, 01 Mar 2026 00:00:00 GMT Prabhavati Shinde, Shraddha Jaiswal, Vidya Tale, Shobha Khilari Pharmacognosy Research Background: The worldwide healthcare system faces significant challenges due to prevalence of chronic wounds worsen by antimicrobial resistant bacteria and polymicrobial biofilm. Objectives: This research aims to unravel antibacterial and antibiofilm potential of bark of Lodhra, Katphal, Bijak and heartwood of Khadir, mentioned in Ayurveda. Materials and Methods: Extracts were prepared by maceration method using ethanol, methanol and water as solvents followed by phytochemicals analysis with… https://www.jrnls.org/phres/19/1/264 https://www.jrnls.org/phres/19/1/264 Sun, 01 Mar 2026 00:00:00 GMT Ankita Ghanshyam Yelne, Vaibhav Mukund Shinde Pharmacognosy Research Background: Urolithiasis remains a recurrent condition that affects patients’ quality of life and causes significant mortality. Once common in Afro-Asian regions, its prevalence is rising in India and other tropical countries. Objectives: This study explores the therapeutic potential of Tamarindus indica L. Seed Hydroalcoholic Extract (TISHE) against urolithiasis. Materials and Methods: In vitro dissolution assays demonstrated TISHE's capacity to dissolve crystals of calcium oxalate and calcium… https://www.jrnls.org/phres/19/1/274 https://www.jrnls.org/phres/19/1/274 Sun, 01 Mar 2026 00:00:00 GMT Syeda Tayyaba Asif, Mohtasheem Ul Hassan, Shah Ali Ul Qader, Madiha Jamshed Pharmacognosy Research Background: Inhibition α-amylase have been reportedly providing a novel way in diabetes and obesity management. Purpose: Research for the last decade has outlined on broad range of health beneficial of various condiments and it is evident that regular spicy food consumption in appropriate quantity is also the reason of reducing risk of death from chronic disorders. Materials and Methods: The preliminary phytochemical screening methanol extracts of P. nigrum fruits and S. aromaticum flower buds… https://www.jrnls.org/phres/19/1/282 https://www.jrnls.org/phres/19/1/282 Sun, 01 Mar 2026 00:00:00 GMT Adelina Simamora, Adit Santoso, Margretha Margretha, Kris Herawan Timotius Pharmacognosy Research Introduction: Akway (Tasmannia piperita), a native Papua plant is known for its benefits as stamina enhancer, antimicrobial, and antioxidant agents, which can be associated to polygodial, its marker compound. Green alternative solvents for polygodial extraction are required. Objectives: In this study, an HPLC-UV method was developed for polygodial analysis from akway barks extracted by deep eutectic solvent. Materials and Methods: Two types of DES were synthesized and used for extraction of… https://www.jrnls.org/phres/19/1/293 https://www.jrnls.org/phres/19/1/293 Sun, 01 Mar 2026 00:00:00 GMT Mrudul Chitrakar Pharmacognosy Research Background: Growing awareness of the health-nutrition interface and demand for convenient yet wholesome foods is rising. Traditional Indian diets, influenced by Ayurvedic principles, emphasize balanced combinations of cereals, pulses, and spices. Objectives: Building on this knowledge, a novel gluten-free, millet-rich multigrain flour, Poshakriti, was developed to meet contemporary nutritional and lifestyle needs. Materials and Methods: Poshakriti was formulated using selected cereals (rice,…