https://www.jrnls.org/phrev New articles published in Pharmacognosy Reviews. en Wed, 11 Mar 2026 00:00:00 GMT https://www.jrnls.org/phrev/20/39/1 https://www.jrnls.org/phrev/20/39/1 Wed, 11 Mar 2026 00:00:00 GMT Mohan Parameswari, Karunamoorthy Jayamoorthy, S. Savitha Pharmacognosy Reviews India's vast biodiversity includes a myriad of medicinal plants that have been utilized in traditional medicine for millennia. Plants have been integral to human health and medicine since ancient times, offering a vast array of pharmacologically active compounds with diverse therapeutic potentials. This review explores the broad spectrum of pharmacological properties exhibited by plants, encompassing antioxidant, antimicrobial, anti-inflammatory, anticancer, and other bioactive activities.… https://www.jrnls.org/phrev/20/39/25 https://www.jrnls.org/phrev/20/39/25 Wed, 11 Mar 2026 00:00:00 GMT Shweta Saboo, Shraddha Sapkal, Vaishanavi Nimbalkar Pharmacognosy Reviews The greatest class of plant-derived polyphenolic chemicals are called flavonoids; they have a wide range of biological effects in both in vitro and in vivo mammalian cell systems. Rutin is one of more prominent flavonoid possessing wound healing, anti-inflammatory, antimicrobial, anti-mutagenic, anti-oxidant, and anti-HIV (Human Immunodeficiency Virus) property. The modification of Rutin’s structure aims to enhance the bioavailability, potency and target specificity. The exploration of… https://www.jrnls.org/phrev/20/39/34 https://www.jrnls.org/phrev/20/39/34 Wed, 11 Mar 2026 00:00:00 GMT Surendra Jugguru, Raju Chatakondu, Shobha Singarapalle, Praveena Thirunalveli Pharmacognosy Reviews Numerous fungal endophytes produce plant-derived chemicals that are pharmacologically useful, making them well-known sources of naturally occurring, biologically active compounds. Alkaloids, coumarins, flavonoids, glycosides, lignans, phenylpropanoids, quinones, saponins, terpenoids, and xanthones, all produced by endophytic fungi, are common plant-derived therapeutic chemicals included in this study. This overview covers research from the initial discovery of Taxol production by endophytic… https://www.jrnls.org/phrev/20/39/41 https://www.jrnls.org/phrev/20/39/41 Wed, 11 Mar 2026 00:00:00 GMT V.S. Thiruvengadarajan, A. Rajasekaran, A. Manimegalai, V. Lal Muthukumar, P. Mathialagan, V.S. Santhosh, T. Thamayanthi Pharmacognosy Reviews Wound healing and inflammation are highly intricate biological processes that work to restore the body’s tissue structure and function after injury. In recent years, growing interest has focused on plant-based bioactive compounds as promising therapeutic options, largely because of their proven effectiveness, safety, and low risk of side effects. A wide range of phytochemicals-such as flavonoids, alkaloids, tannins, saponins, terpenoids, and phenolic compounds-have shown strong wound-healing… https://www.jrnls.org/phrev/20/39/48 https://www.jrnls.org/phrev/20/39/48 Wed, 11 Mar 2026 00:00:00 GMT Heena Sachdeva, Manish Sharma, Maninder M Pharmacognosy Reviews The global outbreak of Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, has presented significant challenges to healthcare systems. Despite the availability of vaccines and antiviral agents, the evolving nature of viral variants necessitates the exploration of complementary strategies. Immunomodulation, particularly through plant-based agents, has emerged as a promising adjunctive approach to manage COVID-19 by restoring immune balance and attenuating hyperinflammation. This review… https://www.jrnls.org/phrev/20/39/54 https://www.jrnls.org/phrev/20/39/54 Wed, 11 Mar 2026 00:00:00 GMT Siddhant Krishna, Sandip Chatterjee, Pawan Kumar Goswami Pharmacognosy Reviews Green tea is rich in catechins, which are polyphenolic chemicals that have strong anticancer effects through pro-apoptotic, anti-inflammatory, and antioxidant processes. They alter a number of molecular pathways, including as those that control the course of the cell cycle, limit angiogenesis, and reduce metastasis. With traditional Chemotherapeutics, Epigallocatechin Gallate (EGCG), the most researched catechin, exhibits synergistic actions that increase efficacy and decrease toxicity.… https://www.jrnls.org/phrev/20/39/63 https://www.jrnls.org/phrev/20/39/63 Wed, 11 Mar 2026 00:00:00 GMT Saurav Talukdar, Suman Kumar, Sarbanga Bezbaruah, Prerana Kashyap, Mohsin Ahmed, Rupjyoti Majumder, Rajsekhar Das, N. Anirudh Singh Pharmacognosy Reviews Hymenocallis littoralis (Jacq.) Salisb., commonly known as the Beach spider lily is a perennial herbaceous plant that belongs to the family Amaryllidaceae; well known for its distinctive ethnomedicinal uses against different serious ailments. The review critically analysed the distribution, traditional uses, phytoconstituents, and pharmacological activity of the plant H. littoralis. All the information described in this study was collected by using the electronic databases comprising PubMed and… https://www.jrnls.org/phrev/20/39/79 https://www.jrnls.org/phrev/20/39/79 Wed, 11 Mar 2026 00:00:00 GMT Roshan Manger, Jun Moni Kalita, Sonam Bhutia Pharmacognosy Reviews The Manger community, one of the indigenous communities living in Sikkim's Gangtok district since ages, has ethnomedical practices that are examined and documented in this study. Important information on 40 medicinal plant species used to cure a variety of illnesses was gathered through field surveys and interviews with five identified traditional healers. Quantitative analysis was employed using the Informant Consensus Factor (ICF) and Use Value (UV). These plants-mostly herbs (70%)-are used… https://www.jrnls.org/phrev/20/39/91 https://www.jrnls.org/phrev/20/39/91 Wed, 11 Mar 2026 00:00:00 GMT Rima El Boukhary, Ali Wassef Assi, Assia Fadi Hachichou, Ali El Nagar, Mohammad Ghalayini, Ahmad Saab, Fathalla Najm, Rayan Heidari, Maha Aboul-Ela Pharmacognosy Reviews Genus Sonchus is a member of the Asteraceae family, contains several species that are well- known for both their medicinal properties and their extensive distribution throughout Europe, Asia, and Africa. The morphology, phytochemistry, and medicinal uses of Sonchus oleraceus and other prominent species are thoroughly reviewed in this article. Their potential as anti-inflammatory, antioxidant, antimicrobial, diuretic, antihypertensive, and cardioprotective agents has been highlighted by recent… https://www.jrnls.org/phrev/20/39/98 https://www.jrnls.org/phrev/20/39/98 Wed, 11 Mar 2026 00:00:00 GMT Vikrant Arya, Ranjeet Kaur Parmar Pharmacognosy Reviews Mutualistic complexities in nature represent an inherent part of adaptation. Interkingdom interactions among organisms helped them to survive against biotic and abiotic stress. Although mutualistic associations have been commonly observed among plants-fungi and plant-virus but the concept of tripartite association involving plants-fungus-virus has not been explored so far. The literature review depicted the presence of interactions between plants and the fungus, in which fungal endophytes/AMF… https://www.jrnls.org/phrev/19/38/127 https://www.jrnls.org/phrev/19/38/127 Fri, 17 Oct 2025 00:00:00 GMT Mueen Ahmed KK Pharmacognosy Reviews The current issue of Pharmacognosy Reviews (Volume 19, Issue 38, July-December 2025) presents a remarkable convergence of traditional botanical knowledge and cutting-edge artificial intelligence applications in drug discovery. This collection of twelve comprehensive reviews and research articles illuminates the evolving landscape of pharmacognosy, where millennia-old plant-based therapeutics meet 21st-century computational methodologies. The editorial board has curated a diverse yet… https://www.jrnls.org/phrev/19/38/130 https://www.jrnls.org/phrev/19/38/130 Fri, 17 Oct 2025 00:00:00 GMT Kaza Pavani, Mude Jagadish Naik Pharmacognosy Reviews Diabetes mellitus is a multifaceted metabolic syndrome that is typified by hyperglycemia of long duration due to the inadequate production or action of insulin. Due to the high expenses of synthetic drugs, coupled with their unwanted effects, increasing interest has been generated to turn to phytochemicals bioactive principles obtained from plants to treat diabetes. Recent research has highlighted the therapeutic potential of several phytochemicals, including alkaloids, glycosides,… https://www.jrnls.org/phrev/19/38/138 https://www.jrnls.org/phrev/19/38/138 Fri, 17 Oct 2025 00:00:00 GMT Sharada Laxman Deore, Ram Chhatrapati Vighne, Bhushan Arun Baviskar Pharmacognosy Reviews The tree species Nothapodytes nimmoniana or Nothapodytes foetida or Mappia foetida of family Icacinaceae commonly known as Ghanera or narakya is of research interest among plant scientist as it contains third most demanding anticancer compound camptothecin and 9-Methoxy camptothecin mainly used for treatment of cervical, breast cancer and few lymphomas. Due to extensive overharvesting to meet market demand of camptothecin, it is now red-listed as per IUCN. More than a 20% decline is reported in… https://www.jrnls.org/phrev/19/38/144 https://www.jrnls.org/phrev/19/38/144 Fri, 17 Oct 2025 00:00:00 GMT Sravani Thimmannagari, Hebbani Nagarajappa Shivaprasad, Gaurav Soni, Madhu Krishnamani Pharmacognosy Reviews Saw palmetto (Serenoa repens) is a palm species with rhizomatous growth, indigenous to the southeastern region of the United States. Traditionally, it has been utilized in herbal medicine for various purposes, with a notable emphasis on supporting men’s health. The berries of saw palmetto contain a range of bioactive components, including fatty acids (such as lauric, oleic, myristic, palmitic, and linoleic acids), phytosterols (β-sitosterol, campesterol, and stigmasterol), and flavonoids… https://www.jrnls.org/phrev/19/38/154 https://www.jrnls.org/phrev/19/38/154 Fri, 17 Oct 2025 00:00:00 GMT Abdullah Faisal Albukhari Pharmacognosy Reviews Neuropsychiatric conditions, including depression and anxiety, pose significant challenges to global health. These issues are often intensified by the limitations of existing pharmacological treatments, which may have delayed effects, incomplete responses, and various side effects. Consequently, there is a growing interest in herbal therapies that provide diverse neuropharmacological benefits. This narrative review aims to critically analyze the potential synergistic interaction between Peganum… https://www.jrnls.org/phrev/19/38/169 https://www.jrnls.org/phrev/19/38/169 Fri, 17 Oct 2025 00:00:00 GMT Jyothi Cheeran Jacob, Rekha Kesavan Nair Pharmacognosy Reviews The genus Cynometra L., belonging to the tropical legume family Fabaceae (subfamily Detarioideae), includes a diverse group of species found in various tropical regions. Several Cynometra species are well known for their role in traditional medicine, especially in areas where they are part of the native plant life. This review highlights and summarizes scientific research on the chemical composition and pharmacological properties of three species native to the southern Western Ghats-Cynometra… https://www.jrnls.org/phrev/19/38/175 https://www.jrnls.org/phrev/19/38/175 Fri, 17 Oct 2025 00:00:00 GMT Abdullah Faisal Albukhari Pharmacognosy Reviews Cancer continues to pose a significant global health challenge, with existing treatment options encountering obstacles such as drug resistance, systemic toxicity, and limited bioavailability. Marine ecosystems present a largely underutilized source of bioactive compounds that possess strong anticancer properties. The advent of Artificial Intelligence (AI) is transforming the landscape of drug discovery by improving the identification, optimization, and delivery processes for these… https://www.jrnls.org/phrev/19/38/186 https://www.jrnls.org/phrev/19/38/186 Fri, 17 Oct 2025 00:00:00 GMT Mohammed Al Saiqali, Syeda Sameena Aziz, Atla Venkateshwar Reddy Pharmacognosy Reviews Phytochemicals, plant-derived bioactive compounds, offer notable health benefits and therapeutic applications. This study extensively covers phytochemicals, their classification, sources, bioactivities, and stereochemistry, categorizing them into groups like flavonoids, alkaloids, saponins, tannins, terpenoids, and lignans. Structure-Activity Relationship (SAR) studies reveal the crucial roles of specific structural features and their biological activities. The nitrogen atoms in alkaloids… https://www.jrnls.org/phrev/19/38/212 https://www.jrnls.org/phrev/19/38/212 Fri, 17 Oct 2025 00:00:00 GMT Abdullah Faisal Albukhari Pharmacognosy Reviews The identification of new anticancer agents is essential for addressing chemotherapy resistance, a significant obstacle in cancer treatment. Soil microorganisms have proven to be a rich source of bioactive substances, and the integration of Artificial Intelligence (AI) is transforming drug discovery by streamlining screening and development processes. This systematic review examines the contributions of microbial metabolites from soil in cancer therapy, their mechanisms against chemotherapy… https://www.jrnls.org/phrev/19/38/225 https://www.jrnls.org/phrev/19/38/225 Fri, 17 Oct 2025 00:00:00 GMT Sapna Tamang, Saurav Moktan Pharmacognosy Reviews In the temperate and sub-temperate zones of the eastern Himalayas, the abundance of medicinal f lora, notably Berberis napaulensis, assumes substantial significance. Berberis napaulensis is a member of the Berberidaceae family, which encompasses 500 species world wide under the genus Berberis, each possessing considerable significance. Notably, one such species, B. napaulensis, is particularly impactful in ongoing medicinal research. This review elucidates the botany, traditional uses,… https://www.jrnls.org/phrev/19/38/236 https://www.jrnls.org/phrev/19/38/236 Fri, 17 Oct 2025 00:00:00 GMT Gauri Shankar Bhardwaj, Aditya Jain, Tanvi Jangid, Ram Niwas Jangir Pharmacognosy Reviews Calotropis procera is a versatile plant widely recognized for its applications in traditional medicine, fodder, fuel, timber, fibre production, and phytoremediation. In recent years, it has also gained attention in nanotechnology research as a green source for nanoparticle synthesis. Green-synthesized nanoparticles have emerged as a major focus due to their environmentally friendly, sustainable, and biocompatible nature. Among various biological sources, plants like C. procera are commonly… https://www.jrnls.org/phrev/19/38/260 https://www.jrnls.org/phrev/19/38/260 Fri, 17 Oct 2025 00:00:00 GMT Gayathri Rajasekharannair Sreekumari, Rajani Kurup Sukumaryamma Remadevi, Konnath Chacko Koshy, Sabulal Baby Pharmacognosy Reviews Western Ghats is a global biodiversity hotspot in India with 7,402 species of flowering plants, of which 1,426 species are endemic. About 40 indigenous tribal communities live in these hill ranges, and they possess several plant-based traditional knowledge practices. This study is a comprehensive review of the ethnomedicinal uses of the plant species endemic to Western Ghats. The ethnomedicinal data of endemic flowering plants were collected from authentic sources such as journals, books,… https://www.jrnls.org/phrev/19/38/267 https://www.jrnls.org/phrev/19/38/267 Fri, 17 Oct 2025 00:00:00 GMT Priyanka Kumari, Ravinesh Mishra, Shalini Sharma, Sweta Thakur Pharmacognosy Reviews Freckles are benign, pigmented macules commonly seen in people with pale skin and high UV exposure. They result from an excess of melanin, which is produced by both genetic and environmental factors. Key enzymes, including tyrosinase and related proteins, are involved in dysregulated melanogenesis, leading to lesions known as ephelides and solar lentigines. Freckles are an important cosmetic problem, and treatment is sought even when they do not result in any medical issues. Common treatments… https://www.jrnls.org/phrev/19/37/1 https://www.jrnls.org/phrev/19/37/1 Sat, 21 Jun 2025 00:00:00 GMT Rohini Chandrakant Kolhe, Priyanka Sudhakar Chaudhari, Manisha Pradeep Khaire, Priyanka Kantaram Ghadage, Archana Sopan More Pharmacognosy Reviews Diabetes, a disorder that is becoming more and more common in the world; however, it affects over 400 million people worldwide. Despite considerable growth in diabetes management, most patients often suffer from a significant number of adverse effects and complications of current treatment plans. Therefore, the best action would be collaborating differently for exploring new therapeutic possibilities. The Glucagon-Like Peptide-1 (GLP-] agonist has a huge role in glucose homeostasis which… https://www.jrnls.org/phrev/19/37/15 https://www.jrnls.org/phrev/19/37/15 Sat, 21 Jun 2025 00:00:00 GMT Dipeksha Macwan, Hiteshkumar V. Patel Pharmacognosy Reviews Protein glycation is an emerging issue that needs attention because it presents a hazard to the health of individuals. Through a sequential succession of non-enzymatic biochemical reactions occurs during glycation of protein, Advanced Glycation End products (AGEs) are formed which makes proteins nonfunctional and through accumulation in the body leading to serious pathogenic conditions. Their accumulation is accelerated in hyperglycemic and oxidative environments, linking them closely to… https://www.jrnls.org/phrev/19/37/23 https://www.jrnls.org/phrev/19/37/23 Sat, 21 Jun 2025 00:00:00 GMT Disha Arora, Shweta Agarwal Pharmacognosy Reviews The genus Ficus, belonging to the Moraceae family, encompasses a diverse group of trees, shrubs and vines, including notable species such as Ficus microcarpa, F. carica (common fig) and F. lyrata (fiddle-leaf fig). Known for their ecological and economic importance, Ficus species play critical roles in their ecosystems, providing habitats for various fauna and contributing to biodiversity. They are characterized by their unique growth habits, intricate leaf structures and distinctive fruiting… https://www.jrnls.org/phrev/19/37/30 https://www.jrnls.org/phrev/19/37/30 Sat, 21 Jun 2025 00:00:00 GMT Renuka Nayak, Neeraj Agrawal, Lowkesh Chandravanshi, Satyawati Rathia, Pallavi Kurre Pharmacognosy Reviews Pregnancy is a very crucial phase in a women’s life. Proper care during this phase is important. It includes systematic diet plan, regular check-ups, healthy regimen, and mindful activities of the pregnant women. In Ayurveda, garbhini paricharya includes samanya ahaar, vihaar and vichaar. And vishesh paricharya includes masanumasik ahaar vidhi, use of garbhasthapak medicines. This has a huge impact on the epigenetics, physical, psychological and behavior of the forthcoming child. Maternal and… https://www.jrnls.org/phrev/19/37/39 https://www.jrnls.org/phrev/19/37/39 Sat, 21 Jun 2025 00:00:00 GMT Sougata Santra, Adib Hussain, Arabinda Nayak Pharmacognosy Reviews People have used native healing plants in different old-school medicine practices worldwide for hundreds of years to fix all sorts of health problems, including ones that mess with the brain and nerves. As science gets better, folks are getting excited again about checking out what these plants can do for brain and nerve issues like feeling worried or down, seizures, trouble sleeping mixed-up thinking, and brain diseases that get worse over time like forgetting everything, shaking a lot or not… https://www.jrnls.org/phrev/19/37/48 https://www.jrnls.org/phrev/19/37/48 Sat, 21 Jun 2025 00:00:00 GMT Abdullah Faisal Albukhari Pharmacognosy Reviews Background:Cancer continues to pose a significant health challenge worldwide, characterized by increasing incidence rates and constraints in current treatment options. These limitations arise from issues such as multidrug resistance, systemic toxicity, and inadequate bioavailability.[1-4] Compounds derived from Peganum harmala and Nigella sativa have shown considerable anticancer activity through various mechanisms, including the induction of apoptosis, interruption of the cell cycle, and… https://www.jrnls.org/phrev/19/37/61 https://www.jrnls.org/phrev/19/37/61 Sat, 21 Jun 2025 00:00:00 GMT Sagarika Khatiwara, Tiewlasubon Uriah Khar, Sonam Bhutia Pharmacognosy Reviews Objectives: This review aims to know the status and gaps in male infertility and enhancement measures in term of traditional utility, In vitro & in vivo studies. Methodology: The data were collected through an extensive literature search from reputed online databases such as PubMed, ScienceDirect, ResearchGate, Google Scholar, Willy, 1library and Core. Results: The results were summarized in the tables and figures. Through an extensive review where a minimum of 20 local plants including 16…