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AJBLS · Lens · Comparative GC-MS Analysis of In-House Prepared and Commercial Market Sample of Avartita Guduchi Taila

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Article · Volume 15, Issue 1 · pp. 112–120

Comparative GC-MS Analysis of In-House Prepared and Commercial Market Sample of Avartita Guduchi Taila

Pankaj Sharma1, Vaibhav Shukla2, Pradnya Prakash Hemke3, Sonali Dayanand Konkeri4, Sanyogeeta Ajay Dixit1, Suhas Kumar Shetty5

  1. 1Department of Rejuvenative & Reproductive Medicine in Ayurveda, KAHER’s Shri BMK Ayurveda Mahavidyalaya, Shahapur, Belagavi, Karnataka, INDIA.
  2. 2Department of Undergraduate Studies, KAHER’s Shri BMK Ayurveda Mahavidyalaya, Shahapur, Belagavi, Karnataka, INDIA.
  3. 3Department of Ayurveda Pharmacology, KAHER’s Shri BMK Ayurveda Mahavidyalaya, Shahapur, Belagavi, Karnataka, INDIA.
  4. 4Department of Ayurveda Internal Medicine, KAHER’s Shri BMK Ayurveda Mahavidyalaya, Shahapur, Belagavi, Karnataka, INDIA.
  5. 5Department of Ayurveda Psychology and Psychiatry, KAHER’s Shri BMK Ayurveda Mahavidyalaya, Shahapur, Belagavi, Karnataka, INDIA.

Abstract

Background: Sneha Kalpana (oil formulation), particularly Avartita Guduchi Taila, enhances Guduchi's (Tinospora cordifolia [Willd.] Miers) therapeutic potency through repeated processing. Comparative phytochemical profiling of classically prepared, hundred-times-processed Shatapaka Guduchi Taila (SGT) and the same-time-processed Market Guduchi Taila (MGT) remains unexplored despite their processing similarities.Materials and Methods: Hundred-cycle Avartita SGT was prepared using Guduchi (kalka), Tila Taila (sneha), and Goksheera (drava) as per Ayurvedic Pharmacopoeia standards at a GMP-certified facility. Market-equivalent MGT was procured from a licensed GMP-certified Ayurveda pharmacy (confidentiality maintained). Samples were analysed by GC-MS (DB-5MS column, helium carrier, NIST library ≥85% match). Peaks were normalised to TIC area % for semi-quantitative comparison by retention time alignment.Results: SGT exhibited cholesterol dominance (49.06%, RT 34.292 min) with 12 major peaks. MGT showed diosgenin predominance (12.839%, RT 50.677 min) across 36 peaks. SGT is enriched in antioxidant squalene/phytosterols, while MGT is dominated by steroidal sapogenins (diosgenin, gitogenin). Common fatty acids confirmed processing identity.Conclusion: Distinct phytochemical profiles despite identical Shatapaka processing underscore raw material variability and thermal transformation effects. SGT favors sustained Rasayana/antioxidant action while MGT excels in acute anti-inflammatory/immunomodulation. Findings advocate for processing standardization for consistent Ayurvedic lipid formulations.

Keywords: Avartana; GC-MS Profiling; Phytochemical Comparison; Shatapaka Guduchi Taila

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