Article · Volume 4, Issue 1 · pp. 20–25
Incidental Detection of HbQ-India during Beta-Thalassemia Screening
Sandhya Iyer1, Suhas Sakhare1, Caesar Sengupta1, A. Velumani1
- 1Hematology Division, Thyrocare Technologies Limited, Plot No.D37/1,TTC Industrial area, MIDC, Turbhe, Navi Mumbai - 400703, INDIA.
Abstract
HbQ-India is a relatively rare hemoglobin variant seen particularly in the Indian subcontinent. In this report we present twenty cases of HbQ-India variant and two cases of HbQ India/Beta- Thalassemia detected in our lab during thalassemia screening tests conducted in camps along with family studies of few cases. These cases were detected over a span of three months from samples screened for thalassemia. In order to perform familial studies, sample of family members of six cases were collected totaling to twenty-two affected cases. Molecular confirmation of the detected HbQ-India trait was done using PCR-ARMS technology. Our study detected frequency of HbQ-India carriers at 1.47%.
Keywords: Frequency; HbQ-India; Hemoglobinopathy
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