Communication · Volume 10, Issue 2 · pp. 86–88

Wound Healing Activity of Herbal Ointment Containing the Extracts of Hibiscus rosa-sinensis Flowers and Curcuma longa Rhizomes

Fazlina Mustaffa¹, Subramani Parasuraman¹, Geethaa Sahgal²

¹Department of Pharmacology, Faculty of Pharmacy, Asian Institute of Medical Sciences and Technology (AIMST) University-Kedah, MALAYSIA..
²Department of Pharmaceutical Technology, Faculty of Pharmacy, Asian Institute of Medical Sciences and Technology (AIMST) University-Kedah, MALAYSIA..

Abstract

Objectives:To evaluate wound healing activity of herbal ointment containing the extracts ofHibiscus rosa-sinensis flowers and Curcuma longa rhizomes. Methodology:H. rosa-sinensis flowers and C. longa rhizomes were extracted using 95% ethanol. H. rosa-sinensisandHibiscus rosa-sinensisointment were prepared using paraffin wax, lanolin and petroleum jelly. Ointment formulation was applied once daily on the excision wound made on Sprague Dawley rats for 20 days. Results:On day 20, the treatment group showed a significant increase in wound contraction which was 93.52 ± 1.38% when compared to control (87.62 ± 1.48%). Conclusion:Herbal ointment exhibited significant wound healing activity in rat excision wound model.

Keywords: Hibiscus rosa-sinensis; Curcuma longa; Wound healing

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