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FRA · Lens · The Rat Fallopian Tubes after Erythropoietin Process

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Article · Volume 12, Issue 2 · pp. 70–73

The Rat Fallopian Tubes after Erythropoietin Process

C Τsompos1, C Panoulis2, A Triantafyllou3, CG Zografos4, E Gerakis5, S Gerakis5, A Papalois6

  1. 1Department of Gynecology, Anticancer Hospital of Thessaloniki “Theageneio”, Thessaloniki, HELLAS (GREECE).
  2. 2Department of Obstetrics and Gynecology, Aretaieion Hospital, Athens University, Athens, Attiki, HELLAS (GREECE).
  3. 3Department of Biological Chemistry, Athens University, Athens, Attiki, HELLAS (GREECE).
  4. 4Department of Surgery, Ippokrateion General Hospital, Athens University, Athens, Attiki, HELLAS (GREECE).
  5. 5Experimental Research Centre, ELPEN Pharmaceuticals, S.A. Inc., Co., Pikermi, Attiki, HELLAS (GREECE).
  6. 6Experimental, Educational and Research Center, ELPEN, European University Cyprus, School of Medicine, CYPRUS.

Abstract

Aim: The capability of erythropoietin (EPO) as antioxidant is exported by the results of 2 preliminary studies, totally evaluating 4 histologic variables of endosalpingeal edema (EE) and oviductal congestion (OC) of the first one and endosalpingeal karyorrhexis (EK) and salpingitis (S) of the other one.Materials and Methods: The antioxidant capability was evaluated upon the 60th reperfusion min (for groups called A and C) and upon the 120th reperfusion min (for groups called B and D). The groups A and B were placebo ones, whereas the groups C and D included EPO as antioxidant.Results: The first pillar study showed that EPO has an oxidant non-significant potency for EE and OC together (p-values=0.5971); grade: “without lesions” alterations 0.0363636 [-0.1017439 - 0.1744712]. The second pillar study showed also an oxidant non-significant potency for EK and S; grade: “without lesions” alterations 0.0090909 [-0.0339659 - 0.0521478] (p-values=0.6715). The 2 above studies were added trying to calculate a common diagnostic value for all the four variables.Conclusion: EPO as antioxidant is a significant recessing agent for the total of the 4 histologic variables; grade: “without lesions” alterations score 0.0136364 [-0.0887489+0.0614762] (p-value=0.7153).

Keywords: Ischemia; Erythropoietin; Endosalpingeal edema; Oviductal congestion; Endosalpingeal karyorrhexis; Salpingitis; Reperfusion

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