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FRA · Lens · Antioxidant activity of Artocarpus altilis (Parkinson) Fosberg leaves

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Article · Volume 4, Issue 2 · pp. 33–39

Antioxidant activity of Artocarpus altilis (Parkinson) Fosberg leaves

Mukesh S. Sikarwar1, Boey Jia Hui1, Kumutha Subramaniam1, Bavani Devi Valeisamy1, Ling Kar Yean1, Kaveti Balaji1

  1. 1Unit of Pharmaceutical Chemistry, Faculty of Pharmacy, AIMST University, Semeling, Kedah Darul Aman, MALAYSIA.

Abstract

Objective: This research was aimed to investigate the antioxidant activity of Artocarpus altilis (Parkinson) Fosberg leaves.Materials and Methods: 2,2 diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay and thiobarbituric acid (TBA) methods were used to determine the antioxidant activity with ascorbic acid as a reference.Results: Total phenolic content was found to be 26.22 mg gallic acid equivalents/g. In DPPH assay, the maximum free radical scavenging activity of the extract was found to be 70.59%. The TBA method also supported the antioxidant potential of the plant extract.Conclusion: From this detailed study, it can be concluded that the ethanolic extracts of A. altilis leaves possess moderate antioxidant property. It may be due to the presence of a modest amount of phenolic compounds in the leaves of this plant. Hence, the ethanolic extract of this plant may not act as first-line antioxidant defense but may be used as supportive antioxidant agent.

Keywords: Antioxidant activity; Artocarpus altilis; 2 2 diphenyl-1-picrylhydrazyl

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