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IJOPP · Lens · Case Report on Anti-Tubercular Drug Induced Hepatoxicity / Modified ATT

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Article · Volume 14, Issue 4 · pp. 294–297

Case Report on Anti-Tubercular Drug Induced Hepatoxicity / Modified ATT

M Saru Khan1, Basil Sunny2, Rithuvaren M Krishnan3

  1. 1Department of Pharmacy Practice, Annai JKK Sampoorani Ammal College of Pharmacy, Erirmedu, Namakkal, Tamil Nadu, INDIA.
  2. 2Manager and Clinical Pharmacologist of Sun Rise Hospital, Kochi, Kerala, INDIA.
  3. 3Annai JKK Sampoorani Ammal College of Pharmacy, Tamil Nadu, INDIA.

Abstract

This case summary focusing on a 67-year male patient admitted in Sun rise Hospital, Kochi with k/c/o active tubercular on cat.2 ATT, now patient came complaint with c/o decreased appetite, food intake, nausea, vomiting and excessive fatigability. The patient was received first line anti tubercular drugs 6 months back RHZE (Rifampin, Pyrazinamide, Ethambutol, and Isoniazid) and discontinued medication 2 months back. Now it is developed a severe hepatitis which is an adverse drug reaction of the Antitubercular drugs.

Keywords: Hepatitis; Adverse drug reaction of anti-TB drug; Treatment; Pulmonary Koch infection; ALT; AST; Modified att

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