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IJOPP · Lens · A Study on Antimicrobial Evaluation of Different Generic and Branded Tablet of Ciprofloxacin HCl Marketed in Wardha District

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Article · Volume 15, Issue 3 · pp. 177–183

A Study on Antimicrobial Evaluation of Different Generic and Branded Tablet of Ciprofloxacin HCl Marketed in Wardha District

Sachin J. Dighade1, Shramika A Chore2, Sunit D Gaurkar1

  1. 1Department of Pharmaceutical Chemistry, Institute of Pharmacy and Research, Badnera, Amravati, Maharashtra, INDIA.
  2. 2Department of Pharmaceutics, Institute of Pharmacy and Research, Badnera, Amravati, Maharashtra, INDIA.
  3. 3Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha, Maharashtra, INDIA.

Abstract

Bacterial infection is responsible for various activity including respiratory, urinary tract, gastrointestinal and abdominal infections. Ciprofloxacin HCl, a second-generation fluroquinolone antibiotic that can treat a number of bacterial infections. The aim of this work was to evaluate antimicrobial activity of different generic and branded drug formulation marketed in Wardha district. i.e. Cifran and Zoxan. All the formulations obtained from the market were in compliance with the control samples in respect of Preformulation study, Disintegration, in vitrodrug release, and antimicrobial potential. Thus, the antimicrobial activity of marketed and control sample was also same shows satisfactory results against Staphylococcus aureusas compare to Escherichia coli, but Staphylococcus aureuswas shows better microbiological assay response as compare toE. coli. Ciprofloxacin HCl Preliminary Branded and Generic drug Cifran Zoxan Antimicrobial potential etc

Keywords: Ciprofloxacin HCl; Preliminary; Branded and Generic drug; Cifran; Zoxan; Antimicrobial potential etc

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