Review · Volume 4, Issue 1 · pp. 1–4

Harnessing the potential of bacterial ghost for the effective delivery of drugs and biotherapeutics

Aditya Ganeshpurkar¹, Ankit Ganeshpurkar¹, Vikas Pandey², Abhishek Agnihotri¹, Divya Bansal², Nazneen Dubey¹

¹Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, Madhya Pradesh, INDIA.
²Pharmaceutics Research Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, Madhya Pradesh, INDIA.

Abstract

It seems to be a necessary need to develop an effective drug carrier system for targeted delivery of pharmaceuticals. Bacterial ghosts are emerging drug delivery platform that are capable of delivery of proteins, antigens, nucleic acids, and pharmaceuticals. Bacterial ghosts are generally produced by lysis of gram-negative bacteria. Pharmaceutically, these ghosts could be utilized to deliver proteins peptides, vaccines, drugs effectively. However, this technology is at initial stage and systematic studies are required to implement such system over humans.

Keywords: Bacterial ghost; biotherapeutics; delivery; drugs

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