Back

JPPCM · Lens · Statistical Study and Analysis of Plasma Proteins

PDF

Article · Volume 11, Issue 3 · pp. 27–32

Statistical Study and Analysis of Plasma Proteins

Bhargavi Reddy Metta1

  1. 1ICHOR Biologics Ltd., Biotechnology Company, Turkapally, Rangareddi, Telangana, INDIA.

Abstract

Serum albumins are important in regulating blood volume by maintaining the oncotic pressure (also known as colloid osmotic pressure) of the blood compartment, bovine serum albumin (cattle serum albumin) or BSA, often used in medical and molecular biology laboratories. Serum albumin is the main protein of human blood plasma. It binds water, cations (such as Ca2+, Na+ and K+), fatty acids, hormones, bilirubin, Thyroxin (T4) and pharmaceuticals (including barbiturates), its main function is to regulate the oncotic pressure of blood. Alpha and beta globulins function as enzymes and proteins that transport compounds in the body. Gamma globulins act as the antibody defence against antigen invasion (Aarons and Rowland, 1981; Aggeler et al., 1967) Gamma globulins are manufactured in cells of the immune system known as lymphocytes and plasma cell, Blood plasma, which is usually about 4% of the body weight, consists of many constituents including H2O, nutrients and metabolites, proteins, various hormones and electrolytes (Aarons and Rowland, 1981). The normal total plasma protein concentration ranges from 5.5 to 8.9 g/dL in domestic-animal species, and it is a complex mixture including simple proteins, glycoproteins and various lipoprotein housands of antibodies (immunoglobulins) are also present in plasma, although under normal conditions the amount of any one is usually quite low.

Keywords: Monoclonal Gammopathy; Plasma Proteins Electrophoresis; Polyclonal Gammopathy; Serum Albumins Serum Proteins

The full text of this article is available as a PDF. Open the PDF.