Article · Volume 4, Issue 2 · pp. 128–130

Isoniazid Induced Liver Injury; A Case Series and Review

Ramatati Anusha¹, Sharad Chand¹, Varun Lal¹, Devarapu Mary Sushmitha¹, Dhypa Sahithi Reddy¹, Siddha Tejaswini¹, Savanthi Chitrahasini¹

¹Department of Pharmacy Practice, TVM College of Pharmacy, Ballari-583103, Karnataka, INDIA.

Abstract

Isoniazid is one of the most common drugs inducing liver injury, identifying and quantification of risk related to the drug is the prime to prevent and treat its occurrence. This case series tried to demonstrate the risk of drug (Isoniazid) by using the various causality assessment scales (RUCAM/CIOMS and Narnajo Algorithm). The cases taken were all males and taking the medication which on course develops the hepatotoxicity. It might be used as the literature for further study in addition similar studies are need to be carried out to understand the risk factor of drug induced liver injury.

Keywords: Isoniazid; Antitubercular therapy; Drug-induced liver injury; Hepatotoxicity

The full text of this article is available as a PDF. Open the PDF.