Article · Volume 1, Issue 5 · pp. 327–330

Comparative Study of Cuscuta reflexa and Cassytha filiformis for Diuretic Activity

Sharma Sakshy², K.K Hullatti², S.M. Prasanna², I.J Kuppast², Sharma Paras²

¹Department of Pharmacognosy, National College of Pharmacy, Shimoga-INDIA
²Department of Pharmacology, National College of Pharmacy, Shimoga-INDIA

Abstract

Aqueous and alcoholic extract of Cuscuta reflexa and Cassytha filiformis were investigated for diuretic activity in Wister rats. The extracts were administered once orally at a dose of 300mg/kg. Frusemide (20mg/kg) was used as standard reference drug and normal saline (25 ml/kg) was used as control. Total urine volume and concentration of Na+, K+ and Cl− excreted in urine were estimated. Aqueous and alcoholic extract of Cuscuta reflexa and Cassytha filiformis exhibited significant diuretic activity and caused marked increase in Na+ and K+ excretion, when compared to saline treated controls. However the diuretic activity of Cassytha filiformis extract was higher than that of Cuscuta reflexa.

Keywords: Cassytha filiformis; Cuscuta reflexa; Diuretic activity; Electrolytes

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