Article · Volume 1, Issue 6 · pp. 435–439
Antioxidant activity of leaves and inflorescence of Eryngium Caucasicum Trautv at flowering stage
Ebrahimzadeh Mohamamd Ali1,2, Nabavi Seyed Fazel1,2, Nabavi Seyed Mohammad1,2
- 1Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, 48189, Sari, Iran.
- 2Department of Physiology / Medical Physics, College of Medicine, Al-Mustansiriya University, P.O. Box 14132 Baghdad, Iraq
Abstract
Methanol extracts of leaves and inflorescence of Eryngium Caucasicum Trautv at flowering stage were investigated for their antioxidant activities employing six in vitro assay systems, i.e. DPPH and nitric oxide radical scavenging, reducing power, linoleic acid and iron ion chelating power. IC50 for DPPH radical-scavenging activity was 0.15 ± 0.01 for leaves and 0.39 ± 0.02 mg ml−1 for inflorescence. Reducing powers of both extracts increased with the increase of their concentrations. Leaves extract showed better activity than Vitamin C (p< 0.05). Extracts showed weak nitric oxide-scavenging activity. Leaves extract exhibited better Fe2+ chelating ability (IC =0.25 mg ml−1) that was comparable with EDTA. (IC =18 μg ml−1). Inflorescence extracts had shown a very weak activity. Extracts showed very good scavenging activity of H2O2. IC50 was 25.5 ± 1.3 for leaves and 177.2 ± 11.6 mg ml−1 for inflorescence, respectively. No antioxidant activity exhibited in linoleic acid test. Extracts exhibited different levels of antioxidant activity in all the models studied.
Keywords: Antioxidant activity; DPPH; Eryngium caucasicum; Free radical scavenging activity; Folin-Ciocalteau
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