Article · Volume 16, Issue 2 · pp. 264–269

Phytochemical Identification of Active Components of Some Medicinal Herbs and Oils Relative to its Biological Activities in Saudi Arabia

Turkyah J. Al-Bogami¹, Elie K. Barbour², Abdulrahman L. Al-Malki^1,2,3, Taha A. Kumosani^1,2,3, Said S. Moselhy⁴

¹Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, SAUDI ARABIA.
²Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, SAUDI ARABIA.
³Production of Bio-Products for Industrial Application Research Group, King Abdulaziz University, Jeddah, SAUDI ARABIA.
⁴Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, EGYPT.

Abstract

Background: Herbal medicine and its bioproducts are rich in bioactive compounds that promising in drug development. These phytochemical constituents may be secondary metabolites that exert high potency.Materials and Methods: This study investigated the phyto-constituents bioactive compounds from the aerial parts of some Saudi medicinal plants using n-hexane extracts (Trichodesma trichodesmoides, Baccharoides schimperi, Anabasis articulateand Achillea fragrantissima) and a mixture of essentials oils in equal ratio (Arnica montana, Chamomile, Salvia officinalis, Oenothera, Walnut leaves and Flaxseed) using GC-MS.Results: The GC-MS analysis of plants and essentials oils revealed the presence of various compounds like terpenoids and vitamins related to its anti-microbial activity, antioxidant and anti-inflammatory activity.Conclusion: It was concluded that, the broad range of terpenoids and vitamins are the main components in the hexane extract. These possess different biological activities. Further studies will be carried out in vivoand in vitroto identify the mechanism of action via signaling pathway.

Keywords: Bioactive compounds; Herbs; Oils; Terpenoids; Vitamins

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