Article · Volume 16, Issue 4 · pp. 887–896
Melezitose a Potential of Bioactive Compound from Aqueous Extract of Indian Satavari: An Web Based in silico Study Utilizing GC-MS Analysis
Sandip Sen1, Kalepu Swathi2, Dubbasi Vishwanath3, Bairam Ravindar4, Mitta Chaitanya2, Srinivas Cherukupally5, Shapuram Tejasree6, Hema Varaha Santhoshi Allu7
- 1Department of Pharmaceutical Chemistry, School of Pharmacy, Guru Nanak Institutions Technical Campus, Ibrahimpattnam, Telangana, INDIA.
- 2Department of Pharmaceutical Chemistry, Bojjam Narasimhulu Pharmacy College for Women, Saidabad, Hyderabad, Telangana, INDIA.
- 3Department of Pharmaceutics, Sree Dattha Institute of Pharmacy, Nagarjuna Sagar Road, Sheriguda, Ibrahimpatnam. Telangana, INDIA.
- 4Department of Pharmaceutical Chemistry, Srikrupa Institute of Pharmaceutical Sciences, Velikatta, Telangana, INDIA.
- 5Department of Pharmacology, Nalla Narsimha Reddy College of Pharmacy, Chowdariguda, Narapally, Korremula X Road, Hyderabad, Telangana, INDIA.
- 6Department of Pharmacology, Vijaya College of Pharmacy, Hayathnagar, Thorrur, Hyderabad, Telangana, INDIA.
- 7Department of Pharmacy, Avanthi Institute of Pharmaceutical Sciences, Cherukupally, Vizianagaram, Andhra Pradesh, INDIA.
Abstract
Background: Historical records indicate that medicinal plants and their components have been utilized for treating diverse conditions since antiquity. Asparagus racemosus, in particular, demonstrates a broad spectrum of therapeutic possibilities.Aim: This study aimed to pinpoint potential bioactive compounds found within the aqueous extract of Asparagus racemosus.Materials and Methods: Gas Chromatography employed to identify the presence of various molecules, while Mass Spectrometry and FTIR analysis validated their molecular structures. The molecule was subjected to thorough scrutiny for its potential as a drug candidate, its biological activity, and its predicted targets using in silico techniques.Results: The aqueous extract stands out as the richest reservoir of carbohydrates and steroidal alkaloids. The molecule Melezitose was found in the highest concentration (37.86%). The identified molecule is a carbohydrate in nature. The computational analysis revealed promising drug-like properties and therapeutic potential for the investigated molecule.Conclusion: It could serve as a viable therapeutic option for addressing multiple disorders.
Keywords: Aqueous extract; Asparagus racemosus; Chromatography; In silico study; Mass spectroscopy; Target analysis
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