Article · Volume 5, Issue 2 · pp. 80–85

Secondary metabolites and bioactivities of Albizia anthelmintica

Tahia K. Mohamed¹, Mahmoud I. Nassar¹, Ahmed H. Gaara^1,2, Walaa A. El-Kashak¹, Iñaki Brouard³, Sayed A. El-Toumy⁴

¹Department of Chemistry of Natural Compounds, National Research Centre, Dokki 12622 Cairo, Egypt
²Department of Chemistry, College of Science, Jazan University, Jazan, Saudi Arabia
³Instituto De Productos Naturales Y Agrobiología, Av. Astrofisico F. Sanchez 3, 38206 La Laguna, Tenerife, Spain
⁴Department of Chemistry of Tannins, National Research Centre, Dokki 12622 Cairo, Egypt

Abstract

Background Albizia species are rich in phenolics and terpenes in the different plant organs. They are widely used in traditional Chinese medicine. So this study investigated the phytochemical and biological activities of Albizia Anthelmintica. Materials and Methods Column chromatography has been performed for the isolation of compounds. Bioactivity studies of A. anthelmintica leaves were carried out on aqueous ethanol extract and some pure compounds were tested for their antioxidant activities. Results Eight compounds have been isolated for the first time from A. anthelmintica. The aqueous ethanol extract of A. anthelmintica showed moderate anti-inflammatory activity and significant for both analgesic and antioxidant activities. Que rcetin-3-O-b-D-glucopyranoside, kaempferol-3-O-b-D-glucopyranoside, kaempferol-3-O-(6b-O -galloyl-b-D-glucopyranoside and quercetin-3-O-(6b-O-galloyl-b-D-glucopyranoside) exhibited potent antioxidant scavenging activity towards diphenyl-picrylhydrazine.

Keywords: Albizia anthelmintica, analgesic, anti-inflammatory, antioxidant, diphenyl-picrylhydrazine, flavonoids

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