jrnls.org logo
Submit

BROWSE ALL JOURNALS

Type 2 letters to search all 19 journals

SEE ALL 19 JOURNALS
Pharmacognosy ResearchNOW IN
Back

PR · Lens · Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

PDF

Article · Volume 7, Issue 1 · pp. 14–17

Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia

Essam Abdel-Sattar1, Dina Abou-Hussein1,2, Frank Petereit3

  1. 1Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt
  2. 2Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia
  3. 3University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Hittorfstraße 56, D-48149 Münster, Germany

Abstract

Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), D-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.

Keywords: Cervical adenocarcinoma; euphol; Euphorbia ammak

The full text of this article is available as a PDF. Open the PDF.