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PR · Lens · The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method

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Article · Volume 7, Issue 1 · pp. 57–65

The optimization of essential oils supercritical CO2 extraction from Lavandula hybrida through static-dynamic steps procedure and semi-continuous technique using response surface method

Hossein Kamali1, Noushin Aminimoghadamfarouj1, Ebrahim Golmakani2, Alireza Nematollahi1

  1. 1Research Center of Natural Products Health, North Khorasan University of Medical Sciences, Bojnurd
  2. 2Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Aim The aim of this study was to examine and evaluate crucial variables in essential oils extraction process from Lavandula hybrida through static-dynamic and semi-continuous techniques using response surface method. Materials and Methods Essential oil components were extracted from Lavandula hybrida (Lavandin) flowers using supercritical carbon dioxide via static-dynamic steps (SDS) procedure, and semi-continuous (SC) technique. Results Using response surface method the optimum extraction yield (4.768%) was obtained via SDS at 108.7 bar, 48.5°C, 120 min (static: 8×15), 24 min (dynamic: 8×3 min) in contrast to the 4.620% extraction yield for the SC at 111.6 bar, 49.2°C, 14 min (static), 121.1 min (dynamic). Conclusion The results indicated that a substantial reduction (81.56%) solvent usage (kg CO2/g oil) is observed in the SDS method versus the conventional SC method.

Keywords: Essential oil; lavandin; lavandula hybrida; response surface method; static-dynamic steps; supercritical carbon dioxide

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