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PR · Lens · Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats

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Article · Volume 9, Issue 3 · pp. 247–252

Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats

Subramani Parasuraman1, Khor Ming Zhen1, Urmila Banik2, Parayil Varghese Christapher1

  1. 1Unit of Pharmacology, Faculty of Pharmacy, AIMST University, Kedah, MALAYSIA.
  2. 2Department of Pathology, Faculty of Medicine, AIMST University, Kedah, MALAYSIA.

Abstract

Objective: To evaluate the effect of curcumin on olanzapine-induced obesity in rats.Materials and Methods: Sprague-Dawley rats were divided into six groups.Results: Curcumin significantly reduced olanzapine-induced body weight gain.Conclusion: Curcumin showed metabolic alteration effects in olanzapine-treated rats.

Keywords: Betahistine; Curcumin; Obesity; Olanzapine

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