Flemingia strobilifera (L.) W. T. Aiton: A Holistic Review on Phytochemistry and Pharmacological Aspects

Abstract

Flemingia strobilifera (L.) W. T. Aiton (Fabaceae) commonly known as “Wild Hops” is an important ethnomedicinal shrub distributed worldwide throughout Asia, Central America and North Eastern Australia. An updated research evidences about this plant have been collected until 2023 from various peer-reviewed research articles through several online databases such as Scopus, Pub Med, Google Scholar, Science Direct and Research Gate. The keywords used during online search were F. strobilifera, plant description, habitat and ecology, ethnobotanical importance, phytochemistry and pharmacological activities. Chemical analysis report indicated the presence of various phytochemicals such as alkane, aurone glycoside, chalcones, epoxy chromenes, flavanones, flavonoid-O-glycosides, flavonols, isoflavonones and sterols. Prevailing studies on pharmacological functions of this plant explained several biological properties such as anthelmintic, analgesic, anti-inflammatory, antioxidant, anxiolytic, anticonvulsant, antiulcerogenic, antimicrobial, antidiabetic, wound healing and estrogenic. Overall, this review discusses the therapeutic promises explored in recent years and highlights the research gaps for forthcoming research.

Keywords: Ethnomedicinal value; Fabaceae; Flemingia strobilifera; Pharmacological activities