Article · Volume 11, Issue 2 · pp. 404–409

Formulation and Evaluation for Solid Lipid Microparticles of Efonidipine

Palanisamy Pethappachetty¹, Rajappa Margret Chandira¹, Meenaa Rajandhran², Dominic Antony Samy³

¹Department of Pharmaceutics, Vinayaka Mission’s College of Pharmacy, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, INDIA.
²Vinayaka Mission’s College of Pharmacy, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, INDIA.
³Sona College of Technology, Salem, Tamil Nadu, INDIA.

Abstract

Design a dosing frequency level for efonidipine and examine its pharmacokinetics and dynamics. Solid Lipid Microparticles were made using efonidipine. ATR-FTIR research 4000 to 400cm-1, SEM analysis, Diffrantional Scanning Calorimetry, Power X-ray diffraction. The current state ofin vitrodrug release research is discussed. Then we’ll look at the ingredients and procedures for making solid lipid microparticles. It is possible to prepare and use microparticles in many ways. Hypotensive solid lipid microparticles with efonidipine showed promise. They all survived three months at 4°C. Oral administration is the most usual technique. Many pharmacological dosage forms are intended to delay drug release. Its systemic circulation and plasma profile are prolonged.

Keywords: Efonidipine; Glyceryl Trilaurate and Egg lecithin; Solid Lipid Microparticles; Stearic acid

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