Formulation and Evaluation for Solid Lipid Microparticles of Efonidipine
Palanisamy Pethappachetty1★, Rajappa Margret Chandira1, Meenaa Rajandhran2, Dominic Antony Samy3★ Corresponding author
- 1Department of Pharmaceutics, Vinayaka Mission’s College of Pharmacy, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, INDIA.
- 2Vinayaka Mission’s College of Pharmacy, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, INDIA.
- 3Sona College of Technology, Salem, Tamil Nadu, INDIA.
CORRESPONDENCE
Palanisamy Pethappachetty
Department of Pharmaceutics, Vinayaka Mission’s College of Pharmacy, Vinayaka Mission’s Research Foundation (Deemed to be University), Salem, Tamil Nadu, INDIA.
Received: 04-06-2022; Revised: 22-06-2022; Accepted: 19-07-2022.
Volume 11, Issue 2 · pp. 404–409 · PUBLISHED · DOI: 10.5530/ajbls.2022.11.54
ABSTRACT
Design a dosing frequency level for efonidipine and examine its pharmacokinetics and dynamics. Solid Lipid Microparticles were made using efonidipine. ATR-FTIR research 4000 to 400cm-1, SEM analysis, Diffrantional Scanning Calorimetry, Power X-ray diffraction. The current state ofin vitrodrug release research is discussed. Then we’ll look at the ingredients and procedures for making solid lipid microparticles. It is possible to prepare and use microparticles in many ways. Hypotensive solid lipid microparticles with efonidipine showed promise. They all survived three months at 4°C. Oral administration is the most usual technique. Many pharmacological dosage forms are intended to delay drug release. Its systemic circulation and plasma profile are prolonged.
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Pethappachetty, P., Chandira, R. M., Rajandhran, M., & Samy, D. A. (). Formulation and Evaluation for Solid Lipid Microparticles of Efonidipine. Asian Journal of Biological and Life sciences, 11(2), 404–409. https://doi.org/10.5530/ajbls.2022.11.54