Volume 6, Issue 1

Research Article

1. Article

   Network Proteins of Angiotensin-converting Enzyme 2 but Not Angiotensin-converting Enzyme 2 itself are Host Cell Receptors for SARS-Coronavirus-2 Attachment

   Sai Sailesh Kumar Goothy, Arun HS Kumar

   pp. 1–5 · DOI: 10.5530/bems.6.1.1 · 2021

   Background:Coronaviruses causing severe acute respiratory syndrome (SARS-CoV) are known to enter the host cells by attaching to the membrane bound angiotensin-converting enzyme 2 (ACE2). Using molecular docking the effic…

   TextPDFLens
2. Article

   Efficacy of Natural Compounds from Tinospora cordifolia against SARS-CoV-2 Protease, Surface Glycoprotein and RNA Polymerase

   Vasanthkumar Sagar, Arun HS Kumar

   pp. 6–8 · DOI: 10.5530/bems.6.1.2 · 2021

   Background: Antiviral activity of natural compounds from Tinospora cordifolia (Amritaballi) were evaluated for their efficacy against SARS-CoV-2 targets involved in virus attachment and replication. Materials and Methods…

   TextPDFLens
3. Article

   Pharmacology of Chloroquine: Potential Mechanism of Action against Coronavirus

   Arun HS Kumar

   pp. 9–10 · DOI: 10.5530/bems.6.1.3 · 2021

   Background:Chloroquine and hydroxychloroquine are recently reported to be effective in treating SARS-CoV-2 illness. The pharmacological mechanisms of this clinical benefit are continued to be explored. Materials and Meth…

   TextPDFLens
4. Article

   Molecular Docking of Natural Compounds from Tulsi (Ocimum sanctum) and neem (Azadirachta indica) against SARS-CoV-2 Protein Targets

   Arun HS Kumar

   pp. 11–13 · DOI: 10.5530/bems.6.1.4 · 2021

   Background: Antiviral activity of tulsi and neem extracts are widely reported. Selected natural compounds from tulsi and neem were hence screened for their efficacy against SARS-CoV-2 targets. Materials and Methods:Using…

   TextPDFLens