Volume 16, Issue 1

Mukesh Maity, Krishna Chandra Maity, Saikat Hazra, Arnab Kheto, Samik Banerjee, Sinchan Das

pp. 1–11 · DOI: 10.5530/fra.20260001 · 2026

It is becoming more well recognized that Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a self-sustaining mucosal ecosystem in which oxidant-antioxidant imbalance, microbial dysbiosis, stromal remodeling, type 2 im…

Chai Zi Wei, Chuah Jia Jun, Subramani Parasuraman

pp. 12–17 · DOI: 10.5530/fra.20260002 · 2026

Background: Gastrodia elata is a traditional Chinese herb used to treat neurological disorders. Gastrodin, its main bioactive component, has been extensively studied for pharmacological effects. This study aimed to evalu…

Pounraj Kanimathi, Karanam Satya Ramya, Rose Mary Kiriyanthan, Arunachalam Radha

pp. 18–25 · DOI: 10.5530/fra.20260003 · 2026

Background: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia, dyslipidaemia, oxidative stress, and progressive tissue damage. This study evaluated the antidiabetic, hypolipidaemic, and an…

Mueen Ahmed KK

pp. 26–27 · DOI: 10.5530/fra.20260004 · 2026

Exercise has long been framed as a double-edged metabolic sword. Vigorous muscular contraction increases mitochondrial oxygen flux and generates Reactive Oxygen Species (ROS) at rates well above resting baseline, and for…

Mohammed Yunus, Mueen KK Ahmed

pp. 28–29 · DOI: 10.5530/fra.20260005 · 2026

The marketing logic behind antioxidant supplements is intuitive almost to the point of being seductive: oxidative stress contributes to aging and disease, fruits and vegetables contain antioxidants, therefore concentrate…

Mueen Ahmed KK

pp. 30–31 · DOI: 10.5530/fra.20260006 · 2026

For half a century, the public has absorbed a simple message: free radicals damage DNA, DNA damage causes cancer, and antioxidants mop up free radicals-therefore antioxidants should prevent cancer. The logic is so intuit…

Mueen Ahmed KK

pp. 32–33 · DOI: 10.5530/fra.20260007 · 2026

Antioxidant dietary supplements continue to be marketed to the public with broad implications of disease prevention and “healthy aging,” yet the weight of randomized evidence has not kept pace with the confidence of the …