jrnls.org logo
Submit

BROWSE ALL JOURNALS

Type 2 letters to search all 19 journals

SEE ALL 19 JOURNALS
Indian Journal of Pharmacy PracticeNOW IN
Back

IJOPP · Lens · Haloperidol-Induced Extrapyramidal Symptoms in a Young Male with Alcohol Dependence Syndrome and Emotionally Unstable Personality Disorder

PDF

Article · Volume 19, Issue 3 · pp. 438–441

Haloperidol-Induced Extrapyramidal Symptoms in a Young Male with Alcohol Dependence Syndrome and Emotionally Unstable Personality Disorder

Arunkumar K1, Haripriya Gurumoorthy2

  1. 1Department of Psychiatry, Government Medical College, Orathur, Nagapattinam, Tamil Nadu, INDIA.
  2. 2Department of Pharmacy Practice, EGS Pillay College of Pharmacy, Nagapattinam, Tamil Nadu, INDIA.

Abstract

Aim/Background: To report a case of haloperidol-induced Extrapyramidal Symptoms (EPSEs) in a young male with alcohol dependence syndrome and emotionally unstable personality disorder.Materials and Methods: A 27-year-old male with chronic alcohol use, seizure disorder, and personality disorder was initiated on haloperidol during complicated alcohol withdrawal. ADRs were assessed using WHO-UMC and Naranjo scales.Results: The patient developed tremors within 24 hr despite prophylactic trihexyphenidyl. Haloperidol was discontinued and replaced with quetiapine, leading to complete symptom resolution. Causality assessment indicated a probable reaction.Conclusion: Even low-dose haloperidol can induce EPSEs in vulnerable populations. Prompt identification, drug withdrawal, and substitution with safer antipsychotics are essential.

Keywords: Haloperidol; Extrapyramidal Symptoms; Alcohol Dependence; Diazepam; Naranjo; Scale; WHO-UMC; Adverse Drug Reaction

The full text of this article is available as a PDF. Open the PDF.