Haloperidol-Induced Extrapyramidal Symptoms in a Young Male with Alcohol Dependence Syndrome and Emotionally Unstable Personality Disorder
Arunkumar K1, Haripriya Gurumoorthy2★★ Corresponding author
- 1Department of Psychiatry, Government Medical College, Orathur, Nagapattinam, Tamil Nadu, INDIA.
- 2Department of Pharmacy Practice, EGS Pillay College of Pharmacy, Nagapattinam, Tamil Nadu, INDIA.
CORRESPONDENCE
Haripriya Gurumoorthy
Department of Pharmacy Practice, EGS Pillay College of Pharmacy, Nagapattinam, Tamil Nadu, INDIA.
Received: 16-12-2025; Revised: 22-01-2026; Accepted: 09-03-2026.
Volume 19, Issue 3 · pp. 438–441 · PUBLISHED · DOI: 10.5530/ijopp.20260588
ABSTRACT
Aim/Background: To report a case of haloperidol-induced Extrapyramidal Symptoms (EPSEs) in a young male with alcohol dependence syndrome and emotionally unstable personality disorder. Materials and Methods: A 27-year-old male with chronic alcohol use, seizure disorder, and personality disorder was initiated on haloperidol during complicated alcohol withdrawal. ADRs were assessed using WHO-UMC and Naranjo scales. Results: The patient developed tremors within 24 hr despite prophylactic trihexyphenidyl. Haloperidol was discontinued and replaced with quetiapine, leading to complete symptom resolution. Causality assessment indicated a probable reaction. Conclusion: Even low-dose haloperidol can induce EPSEs in vulnerable populations. Prompt identification, drug withdrawal, and substitution with safer antipsychotics are essential.
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K, A., & Gurumoorthy, H. (). Haloperidol-Induced Extrapyramidal Symptoms in a Young Male with Alcohol Dependence Syndrome and Emotionally Unstable Personality Disorder. Indian Journal of Pharmacy Practice, 19(3), 438–441. https://doi.org/10.5530/ijopp.20260588