A Rare Clinical Case Report of Hereditary Spherocytosis in a 17-Year-Old Female
Hemalatha Ganjala1★, Ramya Jyothi Padigala1, Jayasri Dimmiti1, Ram Nageswara Rao Gajula1, Mohana Kollipara1★ Corresponding author
- 1Department of Pharmacy Practice, Nirmala College of Pharmacy, Acharya Nagarjuna University, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, INDIA.
CORRESPONDENCE
Hemalatha Ganjala
Department of Pharmacy Practice, Nirmala College of Pharmacy, Acharya Nagarjuna University, Atmakur, Mangalagiri, Guntur, Andhra Pradesh, INDIA.
Received: 12-01-2026; Revised: 06-02-2026; Accepted: 23-03-2026.
Volume 19, Issue 3 · pp. 442–445 · PUBLISHED · DOI: 10.5530/ijopp.20260694
ABSTRACT
A congenital hemolytic condition called Hereditary Spherocytosis (HS) is caused by a lack of Red Blood Cells' (RBCs') plasma membrane protein. The hereditary condition is characterized by splenomegaly, jaundice, and anemia. We describe a case of a 17-year-old female patient who came to the surgical gastrointestinal department complaining of two days of abdominal pain. The patient also had a cold and cough for a few days, but these symptoms were unrelated to the main diagnosis. Laboratory investigations confirmed the diagnosis of hereditary spherocytosis. The patient underwent laparoscopic splenectomy and cholecystectomy as definitive management. Postoperatively, her symptoms resolved, and all the abnormal laboratory parameters normalized at the time of discharge. This case underscores the significance of early recognition and surgical management in enhancing outcomes for patients with hereditary spherocytosis.
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Ganjala, H., Padigala, R. J., Dimmiti, J., Gajula, R. N. R., & Kollipara, M. (). A Rare Clinical Case Report of Hereditary Spherocytosis in a 17-Year-Old Female. Indian Journal of Pharmacy Practice, 19(3), 442–445. https://doi.org/10.5530/ijopp.20260694