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Indian Journal of Pharmaceutical Education and ResearchNOW IN
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IJPER · Lens · Biologically Active Metal Complexes Containing Thiazole core: Synthesis and Spectral Characterization

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Article · Volume 52, Issue 2 · pp. 255–261

Biologically Active Metal Complexes Containing Thiazole core: Synthesis and Spectral Characterization

Nagesh Gunvanthrao Yernale1,2, Bennikallu Hire Mathada Mruthyunjayaswamy1

  1. 1Department of Studies and Research in Chemistry, Gulbarga University, Kalburagi, Karnataka, INDIA.
  2. 2Department of Chemistry, Aditya Women’s Science and Commerce Degree College, Bhalki, Karnataka, INDIA.

Abstract

The present study deals with the synthesis of new ligand N-(4-phenylthiazol-2-yl)-2 (pyridin-2-yl-methylene) hydrazinecarboxamide and it’s Cu (II), Co (II), Ni (II) and Zn (II) complexes and study their antimicrobial activity. The newly prepared compounds are characterized by elemental analysis, FT-IR, 1H NMR, mass, UV-visible and ESR spectral techniques. The elemental analysis data and spectral study indicates octahedral geometry for Cu (II), Co (II) and Ni (II) complexes and tetrahedral geometry for Zn (II) complex. All the compounds were tested for antimicrobial activity, the Cu (II) and Co (II) complexes showed good antimicrobial activity.

Keywords: Schiff base; Thiazole; Pyridine-2-carboxaldehyde; Antimicrobial

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