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IJPER · Lens · Evaluation of Anti-obesity Activity of n-hexane and Methanolic Extracts of Cajanus cajan Linn. Seeds Using Enzymatic Methods

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Article · Volume 57, Issue 3S · pp. s718–s723

Evaluation of Anti-obesity Activity of n-hexane and Methanolic Extracts of Cajanus cajan Linn. Seeds Using Enzymatic Methods

Sakshi Sharma1,2, Anjna Rani2

  1. 1Institute of Pharmaceutical Sciences, Kurukshetra University, Haryana, INDIA.
  2. 2Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, Uttar Pradesh, INDIA.

Abstract

Objectives: To evaluate the in vitro anti-obesity activity of Cajanus cajan Linn. seeds.Materials and Methods: Phytochemical screening and in vitro studies on pancreatic lipase and alpha-glucosidase activity were performed using methanolic and n-hexane extracts at doses of 100-500 mcg/mL.Results: Cajanus cajan Linn. seeds extracts possess dose-dependent inhibitory activities, showing good anti-obesity potential.Conclusion: Preliminary studies reveal significant potential for treating obesity and its complications.

Keywords: Obesity; Cajanus cajan; Pancreatic lipase

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