International Journal of Pharmaceutical Investigation
Volume 15, Issue 2
2025 · pp. 313–674 · 34 articles
- Volume
- 15
- Issue
- 2
- Published
- 2025
- Pages
- 313–674
- Articles
- 34
- Sections
- 2
- ISSN
- Print - 2230-973X, Online -2230-9713
- Journal
- IJPI
In this issue
21–34 of 34Original Article(continued)
- Article
Diptimayee Jena, Asra Jabeen, Akash Deep Mahato, Khush Choudhary, Roshan Mahato, Pakhi Chakraborty, Kirtimaya Mishra
pp. 524–530 · DOI: 10.5530/ijpi.20250120 · 2025
Background Green chemistry, also known as environmentally sustainable chemistry, is an area of study within a field of chemistry with the main goal of reducing the negative effects associated with chemical reactions and …
- Article
Ali Mahzari, Eman H. Khalifa, Ali A Zaeri, Hanan E Alyahyawi, Wanian M Alwanian, Saad M. Wali, Ohood Almuzaini, Yazeed Alshuweishi
pp. 531–542 · DOI: 10.5530/ijpi.20250138 · 2025
Background Cardiovascular diseases comprehend a array of situations that disturb the heart and blood vessels, making them a principal cause of morbidity and mortality worldwide. Dyslipidemia, an imbalance in lipids, such…
- Article
S Mrudhulla, R.T Narendhirakannan
pp. 543–561 · DOI: 10.5530/ijpi.20250143 · 2025
Background Aegle marmelos, commonly known as bael, is a medicinal plant native to India with well-established use in traditional medicine systems. Materials and Methods This study aims to evaluate the antioxidant, anti-i…
- Article
Nirali Doshi, Bijal Prajapati, Lavanya Selvaraj
pp. 562–572 · DOI: 10.5530/ijpi.20250144 · 2025
Background Pharmacovigilance studies analyzing Adverse Drug Reactions (ADRs) play a crucial role in understanding the ADR profile at tertiary care centers. The objective of this study is to identify, analyze and understa…
- Article
Sara Shahid, Maryam Ayesha, Muhammad Fahad, Maryam Mughal, Areej Kainat, Hamda Shakir, Muhammad Ali Tahir, Ansa Ijaz, Qurat-ul-Ain, Saad Saeed Alqahtani, Muhammad Zahid Iqbal
pp. 573–582 · DOI: 10.5530/ijpi.20250152 · 2025
Background A significant number of parents lack knowledge about vaccine-preventable diseases and hold misconceptions regarding the components, side effects and effectiveness of vaccines. A lack of understanding regarding…
- Article
Shweta Sulakude, Nisha Shirkoli
pp. 583–591 · DOI: 10.5530/ijpi.20250153 · 2025
Background Almotriptan Malate is a selective serotonin receptor agonist developed for migraine management in adults. Its bioavailability is 69.1%, with an elimination half-life of 3 hours and has low aqueous solubility. …
- Article
Heena Mittal, Sudhakar Kaushik, Bhawana Bhatt, Assem Babbar
pp. 592–603 · DOI: 10.5530/ijpi.20250154 · 2025
Background Solubility is the most vital parameter in the formulation of different drug delivery systems and one of the core concepts of the formulations. More than 50% of the new drug molecules are facing poor solubility…
- Article
Monish Mukul Das, Sayan Chakraborty
pp. 604–613 · DOI: 10.5530/ijpi.20250155 · 2025
Background Uninterrupted spread of drug-resistant tuberculosis has necessitated prioritization of new and effective antitubercular compound. This investigation aimed to apply in silico methods to find out potential inhib…
- Article
Adarsh Arun Patil, Shailendra Sanjay Suryawanshi
pp. 614–630 · DOI: 10.5530/ijpi.20250067 · 2025
Introduction The growing focus on natural products in drug discovery has led to a deeper investigation of phytochemicals from traditional medicinal plants. Terminalia chebula, known for its broad range of therapeutic use…
- Article
K. Lalitha, M.P. Kusuma
pp. 631–641 · DOI: 10.5530/ijpi.20250116 · 2025
Background Tofacitinib Citrate (TCB) is a selective Janus kinase inhibitor approved by the USFDA for the treatment of Rheumatoid arthritis. However, TCB faces extensive first pass metabolism and causes GI trouble on oral…
- Article
Satish Kumar Dewangan, Shrikant R Inchulkar, Sangeeta Bhagat, Trilochan Satapathy, Nagendra Singh Chauhan
pp. 642–649 · DOI: 10.5530/ijpi.20250151 · 2025
Background Agad Tantra deals with poison and its manifestation, investigation, and treatment. It also deals with medicine having poisonous ingredients which always needs to be evaluated for its toxicity. In India the dru…
- Article
Synergistic Antidepressant Effect of Ginkgo biloba and Withania somnifera Using Experimental Animals
Vinod Ashokdas Bairagi, Rutika Mahendra Kharnare, Kajal Satish Nikam, Yogesh Suresh Ahire
pp. 650–656 · DOI: 10.5530/ijpi.20250013 · 2025
Aim This study involved the antidepressant activity of Ginkgo biloba and Withania somnifera in mice. Depressive disorder is a prevalent psychiatric Condition, affecting 21% of the global population. The currently used dr…
- Article
Rakshita Paladi, Srajana Shetty, Sachin Basavaraj, Pratik Naveenkumar Magadum, Shashidhar Mallikarjun Javali, Shivmantesh Ashok Kittur, Veeresh Hubballi, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Vishwanath Swamy
pp. 657–663 · DOI: 10.5530/ijpi.20251868 · 2025
Background Cardiovascular diseases damage the heart and blood arteries. Cardiovascular disorders account for 31% of all fatalities worldwide, ultimately resulting in death, according to the WHO. A blood clot (thrombosis)…
- Article
Ibrahim Baje Syed, Madhavi Nannapaneni
pp. 664–674 · DOI: 10.5530/ijpi.20251515 · 2025
Aim/Background To develop and validate a sensitive, accurate, simple, precise and cost-effective receptive and understandable method for concurrent evaluation of Gramicidin, Neomycin and Triamcinolone acetonide and their…

