International Journal of Pharmaceutical Investigation volume 15, issue 2 cover
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Cover: International Journal of Pharmaceutical Investigation

International Journal of Pharmaceutical Investigation

Volume 15, Issue 2

2025 · pp. 313–674 · 34 articles

Volume
15
Issue
2
Published
2025
Pages
313–674
Articles
34
Sections
2
ISSN
Print - 2230-973X, Online -2230-9713
Journal
IJPI

In this issue

21–34 of 34

Original Article(continued)

  1. Article

    Diptimayee Jena, Asra Jabeen, Akash Deep Mahato, Khush Choudhary, Roshan Mahato, Pakhi Chakraborty, Kirtimaya Mishra

    pp. 524–530 · DOI: 10.5530/ijpi.20250120 · 2025

    Background Green chemistry, also known as environmentally sustainable chemistry, is an area of study within a field of chemistry with the main goal of reducing the negative effects associated with chemical reactions and …

  2. Article

    Ali Mahzari, Eman H. Khalifa, Ali A Zaeri, Hanan E Alyahyawi, Wanian M Alwanian, Saad M. Wali, Ohood Almuzaini, Yazeed Alshuweishi

    pp. 531–542 · DOI: 10.5530/ijpi.20250138 · 2025

    Background Cardiovascular diseases comprehend a array of situations that disturb the heart and blood vessels, making them a principal cause of morbidity and mortality worldwide. Dyslipidemia, an imbalance in lipids, such…

  3. Article

    S Mrudhulla, R.T Narendhirakannan

    pp. 543–561 · DOI: 10.5530/ijpi.20250143 · 2025

    Background Aegle marmelos, commonly known as bael, is a medicinal plant native to India with well-established use in traditional medicine systems. Materials and Methods This study aims to evaluate the antioxidant, anti-i…

  4. Article

    Nirali Doshi, Bijal Prajapati, Lavanya Selvaraj

    pp. 562–572 · DOI: 10.5530/ijpi.20250144 · 2025

    Background Pharmacovigilance studies analyzing Adverse Drug Reactions (ADRs) play a crucial role in understanding the ADR profile at tertiary care centers. The objective of this study is to identify, analyze and understa…

  5. Article

    Sara Shahid, Maryam Ayesha, Muhammad Fahad, Maryam Mughal, Areej Kainat, Hamda Shakir, Muhammad Ali Tahir, Ansa Ijaz, Qurat-ul-Ain, Saad Saeed Alqahtani, Muhammad Zahid Iqbal

    pp. 573–582 · DOI: 10.5530/ijpi.20250152 · 2025

    Background A significant number of parents lack knowledge about vaccine-preventable diseases and hold misconceptions regarding the components, side effects and effectiveness of vaccines. A lack of understanding regarding…

  6. Article

    Shweta Sulakude, Nisha Shirkoli

    pp. 583–591 · DOI: 10.5530/ijpi.20250153 · 2025

    Background Almotriptan Malate is a selective serotonin receptor agonist developed for migraine management in adults. Its bioavailability is 69.1%, with an elimination half-life of 3 hours and has low aqueous solubility. …

  7. Article

    Heena Mittal, Sudhakar Kaushik, Bhawana Bhatt, Assem Babbar

    pp. 592–603 · DOI: 10.5530/ijpi.20250154 · 2025

    Background Solubility is the most vital parameter in the formulation of different drug delivery systems and one of the core concepts of the formulations. More than 50% of the new drug molecules are facing poor solubility…

  8. Article

    Monish Mukul Das, Sayan Chakraborty

    pp. 604–613 · DOI: 10.5530/ijpi.20250155 · 2025

    Background Uninterrupted spread of drug-resistant tuberculosis has necessitated prioritization of new and effective antitubercular compound. This investigation aimed to apply in silico methods to find out potential inhib…

  9. Article

    Adarsh Arun Patil, Shailendra Sanjay Suryawanshi

    pp. 614–630 · DOI: 10.5530/ijpi.20250067 · 2025

    Introduction The growing focus on natural products in drug discovery has led to a deeper investigation of phytochemicals from traditional medicinal plants. Terminalia chebula, known for its broad range of therapeutic use…

  10. Article

    K. Lalitha, M.P. Kusuma

    pp. 631–641 · DOI: 10.5530/ijpi.20250116 · 2025

    Background Tofacitinib Citrate (TCB) is a selective Janus kinase inhibitor approved by the USFDA for the treatment of Rheumatoid arthritis. However, TCB faces extensive first pass metabolism and causes GI trouble on oral…

  11. Article

    Satish Kumar Dewangan, Shrikant R Inchulkar, Sangeeta Bhagat, Trilochan Satapathy, Nagendra Singh Chauhan

    pp. 642–649 · DOI: 10.5530/ijpi.20250151 · 2025

    Background Agad Tantra deals with poison and its manifestation, investigation, and treatment. It also deals with medicine having poisonous ingredients which always needs to be evaluated for its toxicity. In India the dru…

  12. Article

    Vinod Ashokdas Bairagi, Rutika Mahendra Kharnare, Kajal Satish Nikam, Yogesh Suresh Ahire

    pp. 650–656 · DOI: 10.5530/ijpi.20250013 · 2025

    Aim This study involved the antidepressant activity of Ginkgo biloba and Withania somnifera in mice. Depressive disorder is a prevalent psychiatric Condition, affecting 21% of the global population. The currently used dr…

  13. Article

    Rakshita Paladi, Srajana Shetty, Sachin Basavaraj, Pratik Naveenkumar Magadum, Shashidhar Mallikarjun Javali, Shivmantesh Ashok Kittur, Veeresh Hubballi, Sanatkumar Bharamu Nyamagoud, Agadi Hiremath Vishwanath Swamy

    pp. 657–663 · DOI: 10.5530/ijpi.20251868 · 2025

    Background Cardiovascular diseases damage the heart and blood arteries. Cardiovascular disorders account for 31% of all fatalities worldwide, ultimately resulting in death, according to the WHO. A blood clot (thrombosis)…

  14. Article

    Ibrahim Baje Syed, Madhavi Nannapaneni

    pp. 664–674 · DOI: 10.5530/ijpi.20251515 · 2025

    Aim/Background To develop and validate a sensitive, accurate, simple, precise and cost-effective receptive and understandable method for concurrent evaluation of Gramicidin, Neomycin and Triamcinolone acetonide and their…