Volume 15, Issue 2

Muhammad Abid Mustafa, Aqsa Malik, Eman Javed, Aliza Amjad, Sana Iqbal, Eman Mustafa, Namra Rasheed, Aqsa Shafiq, Muhammad Fahad, Maryam Mughal, Gohar Jaan, Nageen Ramzan

pp. 313–324 · DOI: 10.5530/ijpi.20250024 · 2025

This review explores the role of additive manufacturing, particularly 3D printing, as an innovative approach in targeted drug delivery. It effectively addresses the limitations of traditional methods, such as high costs,…

K N Pooja, D R Bharathi, Syed Sagheer Ahmed, B M Jayanth, K Chandan

pp. 325–333 · DOI: 10.5530/ijpi.20250047 · 2025

Precision medicine in diabetes management is a groundbreaking approach that tailors treatment strategies to individual patients, moving beyond the one-size-fits-all model. It leverages genetic, molecular and lifestyle da…

Lakshmi Prasanthi Nori, Maddala Lohitha, Rama Rao Vadapalli, Brahmaiah Bonthagarala, Sudarshan Rao Nagineni, Venkateswara Raju Kalidindi

pp. 334–360 · DOI: 10.5530/ijpi.20250100 · 2025

Artificial Intelligence (AI) is ushering in a transformative era for personalized medicine by customizing therapeutic interventions based on individual patient profiles, including genetic information and environmental in…

Kamalesh Dilip Mali, Durgesh Tulshiram Shinde, Kalpesh Ravindra Patil

pp. 344–360 · DOI: 10.5530/ijpi.20250146 · 2025

Solubility enhancers are one way to get around the difficulties with medication absorption and dissolution in oral drug delivery, since many novel active pharmaceutical components are not well soluble in water. The effic…

Saniya Makkad, Mujibullah Sheikh, Sanskruti Shende, Pranita Jirvankar

pp. 361–376 · DOI: 10.5530/ijpi.20251676 · 2025

Pharmaceutical excipients are integral to therapeutic formulations; their importance has grown from inert and economical materials to components that make up 80-90% of the finished product. This review examines the excip…

Sanjiv Kumar Gupta, Neelesh Chaubey

pp. 377–387 · DOI: 10.5530/ijpi.20251793 · 2025

Nanoemulsion-based nanogels have emerged as a promising approach for treating fungal infections due to their unique properties. Nanoemulsions are fine oil-in-water or water-in-oil dispersions stabilized by surfactants, c…

Bysani Suresh Babu, Nalanda Revu Baby, Sumanta Mondal

pp. 388–396 · DOI: 10.5530/ijpi.20250004 · 2025

Objectives This study describes developing and validating a novel method using LC-MS/ MS to measure the concentration of Momelotinib in rat plasma. Materials and Methods The pharmacokinetic applicability of the process w…

Bipin Shaji, Juno Jerold Joel, Raghava Sharma, Shraddha Shetty

pp. 397–406 · DOI: 10.5530/ijpi.20250019 · 2025

Background Hypothyroidism is characterized by an underactive thyroid gland. As thyroid hormones are essential for regulating metabolism, disruptions in secretions can cause metabolic syndrome. This study is to assess the…

Shamita Shyam Sail, Akshata Gore, Arfa Anwar Sayed, Mohd Ramish Khan, AHM Viswanatha Swamy, BM Dayana, Sanatkumar Bharamu Nyamagoud

pp. 407–416 · DOI: 10.5530/ijpi.20250035 · 2025

Background Materiovigilance is important for checking the safety and effectiveness of medical devices. There isn't much research on how pharmacy students understand and perceive about materiovigilance. To understand this…

KM Sowmya, RT Narendhirakannan

pp. 417–433 · DOI: 10.5530/ijpi.20250039 · 2025

Background Nanoparticles, particularly those from natural sources like E. cardamomum, have garnered significant interest due to their unique physicochemical characteristics and potential applications in medicine. Materia…

Prasad Dilip Kadam, Ganpat Ram Nagargoje, Abhay Shivajirao Bondge, Kalimoddin Inayatsab Momin, Sharad Pandit Panchgalle, Vijaykumar Shivdas More

pp. 434–442 · DOI: 10.5530/ijpi.20250040 · 2025

Background The study focuses on the synthesis of novel 4-Hydrazinyl-7H-Pyrrolo[2,3-d] Pyrimidine (HPP) derivatives using microwave-assisted synthesis starting from substituted benzaldehydes (a-j) and HPP in the presence …

Mithun Bandivadekar, Ashwini Madgulkar, Syed Mubashir Rashid, Ranjitkumar Padakanti, Vedanti Godbole

pp. 443–453 · DOI: 10.5530/ijpi.20250042 · 2025

Background Anti-retroviral drugs are challenging formulation scientists due to their poor solubility problem. This criticality increases when the drug has to be delivered by a vaginal route where the availability of flui…

Aneesha Addanki, Rama Rao Nadendla, Vijaya Kishore Kanakaraju

pp. 454–461 · DOI: 10.5530/ijpi.20250068 · 2025

Background Alzheimer's disease has become a serious health problem in recent years. Certain acetylcholinesterase inhibitors have been shown to have anti-Alzheimer's properties. In the current work, a number of oxazepine …

Revathi Sundaramoorthi, Anitha Pavadai, Jenifer Sathappan, Senthil Rajan Sivakumar

pp. 462–470 · DOI: 10.5530/ijpi.20250074 · 2025

Background The solubility of medications significantly affects their absorption and therapeutic effectiveness. Drugs with poor solubility often faces challenges in formulation development leading to low bioavailability a…

Suresh Yerramsetty, Lavanya Ayyagari, Venkata Krishna Kanth Makani, Jolly Janette Mendonza, Suchitra Maheswari Ajjarapu, Ahmed Kamal, Smita C. Pawar, Manika Pal Bhadra

pp. 471–481 · DOI: 10.5530/ijpi.20250079 · 2025

Parkinson’s Disease (PD) is the second most prevalent form of neurodegenerative disorder distinguished by progressive and specific loss of dopaminergic neurons in the Substantia Nigra (SNPc) resulting in abnormal movemen…

Dipti Gohil, Ujjaval Patel, Priyank Patel, Nirmal Shah, Sunil Kardani

pp. 482–489 · DOI: 10.5530/ijpi.20250086 · 2025

Background Rheumatoid arthritis causes chronic joint pain and inflammation, significantly impacting quality of life. Current treatments are limited, with oral Leflunomide commonly used. However, prolonged oral administra…

Jawahar Natarajan, Pavalan Krishnan, Sebatini Sinsi Arokianathan, Sharuni Sivakumar, Parish Vendar Saravanan, Roshan Prasad Rao

pp. 490–497 · DOI: 10.5530/ijpi.20250087 · 2025

Objectives Sunscreen cosmeceuticals play a crucial role in protecting the skin from dangerous ultraviolet radiation, which is linked to various dermatological diseases and skin cancers. Avobenzone is extensively used org…

Balakrishna Talamanchi, Lakshman Kumar Dogiparthi, Bala Sree Sanjeevi Pusala, Roshni Patan, Vamsi Abhiram Yadlapalli, Vinay Simhadri, Shahid Hussain Shaik, Yasaswini Vakkalagadda

pp. 498–507 · DOI: 10.5530/ijpi.20250095 · 2025

Introduction The goal of this study was to develop and evaluate Bosentan transdermal patches for the treatment of Pulmonary Arterial Hypertension (PAH), which is defined as an abnormally high blood pressure in the arteri…

Rhea Surana Lalit, K Karthika, Kavitha Ramasamy

pp. 508–515 · DOI: 10.5530/ijpi.20250103 · 2025

Objectives: Zolpidem, a novel non-benzodiazepine sedative, has shown antioxidant, muscle relaxant, anti-convulsant and anti-anxiety properties. The Objective of our study is to evaluate it’s in vitro anti-inflammatory ac…

Sunil Rayudu, Medikonda Manoranjani, D Anitha

pp. 516–523 · DOI: 10.5530/ijpi.20250109 · 2025

Background An accurate, rapid, inexpensive, and straightforward, reliable simultaneous assay technique was developed and demonstrated to evaluate Levodopa and Benserazide using RP-HPLC. Materials and Methods The suggeste…