Volume 3, Issue 4

Original Research Article

1. Article

   Cavamax W7 composite psoralen ethosomal gel versus cavamax W7 psoralen solid complex gel for topical delivery: A comparative evaluation

   Smriti Kumari, Kamla Pathak

   pp. 171–182 · DOI: 10.4103/2230-973X.121284

   Aim: The present research work was aimed to formulate and characterize psoralen-encapsulated cavamax W7 composite ethosomal gel and compare its in vitro and ex vivo behavior against psoralen-cavamax W7-complex reference …

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2. Article

   Formulation, characterization, in vitro, in vivo, and histopathological evaluation of transdermal drug delivery containing norfloxacin and Curcuma longa

   Kamal Dua, Srikumar Chakravarthi, Dinesh Kumar, Ravi Sheshala, Gaurav Gupta

   pp. 183–187 · DOI: 10.4103/2230-973X.121287

   Objective:In an attempt for better treatment of bacterial infections and burn wounds, semisolid formulations containing norfloxacin (NF) and natural wound healing agent Curcuma longa were prepared. The rationale behind e…

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3. Article

   Teucrium polium L. extract adsorbed on zinc oxide nanoparticles as a fortified sunscreen

   Mehdi Ansari, Fariba Sharififar, Maryam Kazemipour, Zarrin Sarhadinejad, Hamid Mahdavi

   pp. 188–193 · DOI: 10.4103/2230-973X.121289

   Introduction: Zinc oxide nanoparticles (ZnOn) have been used as carriers and sun-protecting agents for Teucrium polium L. extract to enhance sun protection. ZnOn was synthesized by hydrolyzing zinc acetate using sodium h…

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4. Article

   Zinc cross-linked hydroxamated alginates for pulsed drug release

   Neha S Raut, Prasad R Deshmukh, Milind J Umekar, Nandkishor R Kotagale

   pp. 194–202 · DOI: 10.4103/2230-973X.121292

   Introduction: Alginates can be tailored chemically to improve solubility, physicochemical, and biological properties and its complexation with metal ion is useful for controlling the drug release. Materials And Methods:S…

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5. Article

   Formulation and evaluation of sustained release enteric-coated pellets of budesonide for intestinal delivery

   Mihir K Raval, Riddhi V Ramani, Navin R Sheth

   pp. 203–211 · DOI: 10.4103/2230-973X.121294

   Introduction:The aim of present work was to develop intestinal-targeted pellets of Budesonide, a potent glucocorticoid, used for the treatment of ulcerative colitis and Crohn’s disease by extrusion and spheronization met…

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6. Article

   In vitro and in vivo assessment of piroxicam incorporated Aloe vera transgel

   Vinesha Velam, Prasanna Raju Yalavarthi, Sundaresan CR, Vandana KR, Thushara Bindu Dudala, Haritha Kodavatikanti, Harini Chowdary Vadlamudi

   pp. 212–216 · DOI: 10.4103/2230-973X.121303

   Background: The aim of the study was to develop piroxicam-Aloe vera gel (PAG) formulation and make a pharmacodynamic evaluation of the formulation. Materials and Methods:The gel was prepared by using carbopol 934 as gell…

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7. Article

   Development and evaluation of 6-mercaptopurine and metoclopramide polypill formulation for oral administration: In-vitro and ex vivo studies

   Rajani Chowdhary, Roopa S Pai, Gurinder Singh

   pp. 217–224 · DOI: 10.4103/2230-973X.121306

   Introduction:The present investigation was to develop a polypill of 6-mercaptopurine and metoclopramide. A polypill with delayed release granules of an anticancer and immediate release mucoadhesive tablet of antiemetic m…

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8. Article

   Evaluation of in vivo efficacy and toxicity of prednisolone- loaded hydrogel-based drug delivery device

   Amit Kumar De, Plaban Bhattacharya, Sriparna Datta, Arup Mukherjee

   pp. 225–233 · DOI: 10.4103/2230-973X.121308

   Drugs prescribed for the treatment of moderate to severe inflammatory bowel disease (IBD) are associated with number of side effects. Targeted drug delivery is essential for the treatment of inflammatory bowel disease in…

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