Volume 6, Issue 4

Smita Raghuvanshi, Kamla Pathak

pp. 181–193 · DOI: 10.4103/2230-973X.195923

Introduction: The study was aimed at the development of low-density gastroretentive bioadhesive microsponges of cinnarizine by two-pronged approach (i) coating with bioadhesive material and (ii) exploration of acconon MC…

Krishnamoorthy Venkateskumar, Subramani Parasuraman, Raju Gunasunderi, Krishnan Sureshkumar, M. Muralidhar Nayak, Syed Adnan Ali Shah, Khoo Kassen, Heng Wei Kai

pp. 194–200 · DOI: 10.4103/2230-973X.195925

Objective: The objective of this study is to provide a mechanistic insight into solubility enhancement and dissolution of acyclovir (ACY) by polyethylene glycol20000 (PEG20000). Materials and Methods:Solid dispersions wi…

Poluri Koteswari, G. Puja Sravanthi, M. Mounika, S. K. Mohammed Rafi, K. Nirosha

pp. 201–206 · DOI: 10.4103/2230-973X.195927

Objective: The present investigation involves the development of zolmitriptan oral soluble film (OSF) formulations and optimization with quality by design (QBD) using natural polymers and evaluation. Materials and Method…

Naveen Kanthamneni, Satyanarayana Valiveti, Mita Patel, Heather Xia, Yin‑Chao Tseng

pp. 218–224 · DOI: 10.4103/2230-973X.195931

Introduction: The majority of drugs obtained through synthesis and development show poor aqueous solubility and dissolution velocity, resulting in reduced bioavailability of drugs. Most of these problems arise from formu…

Guo Huimin, Fu Xiaoying, Du Hongwei, Cong Wei, Meng Xiangcai

pp. 225–230 · DOI: 10.4103/2230-973X.195932

Introduction: The quality of radix scutellariae is particularly associated with environmental stresses, but detailed mechanisms remained unclear. Plant under unfavorable situation generates redundant reactive oxygen spec…

Jafar Fattahi‑asl, Mojtaba Karbalaee, Masoud Sanatizadeh, Payam Amini

pp. 231–237 · DOI: 10.4103/2230-973X.195933

Objective: The aim of this study was to compare the effects of radiofrequency radiation (RF) in synergism with gold (Au) and silver (Ag) nanoparticles (NPs) on the survival fraction of human normal kidney (HNK) and human…

N. Arjun, D. Narendar, K. Sunitha, K. Harika, B. Nagaraj

pp. 238–246 · DOI: 10.4103/2230-973X.195951

Purpose:Osmotic devices are the most promising strategy-based systems for controlled drug delivery. By optimizing formulation and processing parameters, possible to develop osmotic systems to deliver drugs at predetermin…