Article · Volume 9, Issue 3 · pp. 128–134

Quality Standards and Antioxidant Activity of Siddha Formulation Cuvacakutori Chooranam

Achintya Kumar Mandal¹, Ramachandran Shakila¹, Sujith Thatipelli¹, Mattummal Rubeena¹, Kopala Narayanan Sunilkumar¹, Arumugam Thilagam¹, Rethinam Ganesan¹

¹Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.

Abstract

Objectives: To evaluate quality standards and to screen antioxidant activity of Cuvacakutori Chooranam (CC) a poly herbomineral Siddha formulation.Methods: The drug was prepared with authenticated ingredients. Powder microscopic, phytochemical, physicochemical, HPTLC fingerprint profiling (n-hexane, successive chloroform, successive ethanol), total phenol and flavonoid estimation, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scav- enging and superoxide scavenging activities of CC were studied.Results: Microscopic studies revealed diagnostic features to identify the formulation using microscope. Preliminary phytochemical screening revealed the presence of different secondary metabolites, unique chromatographic fingerprint and antioxidant activities.Conclusion: The powder microscopic characters and the evolved physicochemical data arrived could serve as a reference tool for quality control. The presence of different categories of phytochemicals and antioxidant activity of the drug gives broad scope for further efficacy studies of this drug.

Keywords: Respiratory diseases; Cuvacakutori chooranam; Standardization; HPTLC; Antioxidant

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