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International Journal of Pharmaceutical InvestigationNOW IN
Article

Quality Standards and Antioxidant Activity of Siddha Formulation Cuvacakutori Chooranam

Achintya Kumar Mandal1, Ramachandran Shakila1★, Sujith Thatipelli1, Mattummal Rubeena1, Kopala Narayanan Sunilkumar1, Arumugam Thilagam1, Rethinam Ganesan1★ Corresponding author

  1. 1Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.

CORRESPONDENCE

Ramachandran Shakila

Siddha Central Research Institute, (Central Council for Research in Siddha, Ministry of AYUSH, Government of India), Anna Hospital Campus, Arumbakkam, Chennai, Tamil Nadu, INDIA.

shakilasiva@gmail.com

Volume 9, Issue 3 · pp. 128–134 · PUBLISHED · DOI: 10.5330/ijpi.2019.3.24

View on IJPI original site ↗

ABSTRACT

Objectives:To evaluate quality standards and to screen antioxidant activity of Cuvacakutori Chooranam (CC) a poly herbomineral Siddha formulation. Methods: The drug was prepared with authenticated ingredients. Powder microscopic, phytochemical, physicochemical, HPTLC fingerprint profiling (n-hexane, successive chloroform, successive ethanol), total phenol and flavonoid estimation, 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scav- enging and superoxide scavenging activities of CC were studied. Results: Microscopic studies revealed diagnostic features to identify the formulation using microscope. Preliminary phytochemical screening revealed the presence of different secondary metabolites, unique chromatographic fingerprint and antioxidant activities. Conclusion:The powder microscopic characters and the evolved physicochemical data arrived could serve as a reference tool for quality control. The presence of different categories of phytochemicals and antioxidant activity of the drug gives broad scope for further efficacy studies of this drug.

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    Mandal, A. K., Shakila, R., Thatipelli, S., Rubeena, M., Sunilkumar, K. N., Thilagam, A., & Ganesan, R. (). Quality Standards and Antioxidant Activity of Siddha Formulation Cuvacakutori Chooranam. International Journal of Pharmaceutical Investigation, 9(3), 128–134. https://doi.org/10.5330/ijpi.2019.3.24