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JPP · Lens · Ceftriaxone-Induced Thrombocytopenia in a Patient with Bacterial Meningoencephalitis

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Article · Volume 12, Issue 4 · pp. 175–176

Ceftriaxone-Induced Thrombocytopenia in a Patient with Bacterial Meningoencephalitis

Anjaly A. Kumar1, Vani Vijay1, M. Arya1, P. K. Vasant1, Subhash Chandra1, Abhishek C. Menon1

  1. 1Departments of Pharmacy Practice and1Internal Medicine, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.

Abstract

Drug-induced thrombocytopenia is a rare and life-threatening condition. It is mainly caused by the initiation of drug-dependent platelet reactive antibodies that leads to the accelerated platelet destruction. Ceftriaxone is a third-generation cephalosporin, which has rarely reported cases of drug-induced immune thrombocytopenia. Here, we report a case of ceftriaxone-induced thrombocytopenia after the initiation of antibiotic therapy for bacterial meningoencephalitis based on the laboratory findings with the initiation and discontinuation of ceftriaxone.

Keywords: Ceftriaxone; drug-induced immune thrombocytopenia; meningoencephalitis; thrombocytopenia

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