Article · Volume 3, Issue 2 · pp. 200–201

Docetaxel-induced hand foot syndrome: “No dose is a safe dose”

Ankit Jain¹, Biswajit Dubashi¹

¹Department of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry 6, India Case Report.

Abstract

Docetaxel is an important chemotherapeutic agent used in the management of many solid tumors. The most important side effect of this drug is myelosupression. We report a case of carcinoma breast that developed severe hand-foot syndrome at 75 mg/m2 doses of docetaxel. The exact mechanism of this side effect in not known. All the physicians using this drug must be aware of this side effect.

Keywords: Acral erythema breast cancer; docetaxel; hand foot syndorme; palmo-plantar dysesthesia

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