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JPP · Lens · Angioedema due to fixed dose combination of telmisartan plus ramipril

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Article · Volume 5, Issue 3 · pp. 214–216

Angioedema due to fixed dose combination of telmisartan plus ramipril

Vishal R. Tandon1, Annil Mahajan2, Vijay Khajuria1, Zahid H. Gillani1

  1. 1Department of Pharmacology and Therapeutic, College, Jammu, Jammu and Kashmir, India Case Report.
  2. 2Department of General Medicine, Government Medical College, Jammu, Jammu and Kashmir, India Case Report.

Abstract

The risk for angioedema has been suggested lower with angiotensin receptor blockers (ARBs) than with angiotensin‑converting enzyme inhibitors (ACEIs) or aliskiren. Many isolated reports do exist, reporting angioedema with ARBs such as olmesartan, valsartan, losartan and telmisartan. To the best of our knowledge this is the first case report of telmisartan plus ramipril fixed dose combination leading to angioedema from India questioning the rationality of ARBs plus ACEIs combination in the treatment of hypertension.

Keywords: Angiotensin‑converting enzyme inhibitors; angiotensin receptor blockers; fixed dose combination; Telmisartan; Ramipril

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