Article · Volume 9, Issue 2 · pp. 104–108

Adverse Drug Reactions at an Addiction Psychiatry Center: A Cross‑sectional Analysis

Siddharth Sarkar¹, Rakesh K. Chadda¹, Anusha Thota², Naveen Kumar Dhagudu¹, Thota Prasad²

¹Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, India.
²Pharmacovigilance Programme of India, Indian Pharmacopoeia Commission (IPC), Ghaziabad, Uttar Pradesh, India.

Abstract

Objective: To perform a cross sectional analysis of anticipated and unanticipated adverse drug reactions occurring at an addiction psychiatry center.Materials and Methods: This observational analysis presents data on the ADRs reported by the health‑care professionals at a tertiary care public‑funded treatment center. The types of ADRs encountered over a period of 12 months are presented along.Results: A total of 251 ADRs were encountered in patients with substance use disorders. Of them, 23% were unlabeled adverse reactions. At the center, tramadol was the most common medication implicated for ADR, followed by naltrexone and disulfiram. The most common adverse event reported was loss of appetite (n = 26). According to the system organ classification, gastrointestinal (18.7%) and psychiatric symptoms (18.7%) were the most common systems implicated.Conclusion: The current findings provide opportunities for sensitization of health‑care professionals. This will help in promoting safer drug use in the field of addiction psychiatry.

Keywords: Causality assessment; National Drug Dependence Treatment Centre; pharmacovigilance; suspected adverse drug reaction

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