Drug Delivery Tailored for the Need– Case Series of Oral Lichen Planus

Abstract

Lichen planus is an inflammatory mucocutaneous disorder. The pathogenesis of lichen planus is predominantly T cell mediated. The condition is associated with it are hepatitis C, graft versus host disease, medications [antiarrythmic drugs, anti-hypertensive], dental materials [amalgam restoration] etc. Immune modulators have been widely used in the management of lichen planus. Corticosteroids are the most widely used among them. There is various mode of delivering corticosteroids in oral lichen planus. The systemic administration is reported to cause more adverse drug reaction when compared to local drug delivery systems. The case series describes three cases of lichen planus at different sites. It also high lights the site-specific treatment applied in them.

Keywords: Lichen planus; Local drug delivery; Corticosteroids; Systemic steroids