Article · Volume 13, Issue 3 · pp. 312–314
Amphotericin B Induced Thrombophlebitis: A Case Report
Bandaru Yeswanth Raja1, Manithottiyle Angelo Simon1, Kolli Sowjanya1, K.T. Jayakumar2, Thangavel Mahalingam Vijayakumar1
- 1Department of Pharmacy Practice, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu, Tamil Nadu, INDIA.
- 2Department of General Medicine, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Kanchipuram, Kattankulathur, Chengalpattu Tamil Nadu, INDIA.
Abstract
Amphotericin B is most widely used antifungal drug of choice. We report a case of a 56-year-old man developed pain and skin swelling over right forearm at the intravenous access site during amphotericin B administration treatment given for mucormycosis, the post-operative of sinuses. After 4 hours of affected period, amphotericin B was administration. A well revealed thrombophlebitis of the right forearm was noted. The systemic reaction was assessed based on the naranjo algorithm and was found to be probable. The safety profile of amphotericin B and its adverse effects must be monitored on long term treatment usage.
Keywords: Thrombophlebitis; Amphotericin B; Adverse drug reaction; Pharmacovigilance; Mucormycosis
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