Review Article on Effects of Moringa on Central Nervous System

Abstract

Moringa oleifera is a plant of high value because of its wide range of applications, it is an indigenous plant widely distributed in India and other parts of the world. It contains a wide variety of phytoconstituents viz. flavonoids, saponins, sterols, anthraquinones, tannins and terpenoids. It possesses antidiabetic, antitumor, antibacterial, antihypertensive and other activities of medicinal use. Studies have also found its activity on central nervous system, in neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, neuropathic pain, Multiple sclerosis, ischemia, depression and it has shown to promote neurite outgrowth, and reported to possesses neuroprotective action. Here we review the potential activity of Moringa on central nervous system and against various neurodegenerative disorders.

Keywords: Alzheimer’s disease; Depression; Moringa; Neurodegenerative diseases; Neuronal development; Oxidative stress