Potential Food Interactions of Antibiotics and Risk of Antimicrobial Resistance: A Database Research Study

Abstract

Objectives: The present study describes about the Antibiotic-Food Interactions (AFI) and development of Antimicrobial resistance (AMR).Materials and Methods: The Micromedex medication database was used to find and identify potential antibiotic interactions. Micromedex is a trustworthy drug database that used to research medications, interactions, diseases, and dose estimations.Results: As a result, a total of 68 AFIs were obtained, including major, moderate, and Minor AFIs among them. AMR-causing interactions were found in 34 of the 68 AFIs (50%). Only 3 (4.41%) of these 34 (50%) interactions were minor, whereas the remaining 31 (45.58%) were moderate. Only moderate and minor interactions were expected to induce AMR evolution; no major interactions were found to be unrelated to AMR development.Conclusion: Antimicrobial resistance is an important public health concern throughout the world. A pharmacist is a healthcare expert who analyzes a prescription for possible medication interactions and eliminates them in order to improve the patient’s prognosis.

Keywords: Antimicrobial resistance; Drug-food interactions; Antibiotics; Clinical pharmacist