Article · Volume 2, Issue 4 · pp. 365–368
Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract
Kumar D1, Kumar S1, Singh J1, Narender N1, Rashmi R1, Vashistha BD2, Singh N3
- 1Institute of Pharmaceutical Sciences, INDIA.
- 2Department of Botany, Kurukshetra University, Kurukshetra, Haryana, INDIA.
- 3Department of Botany, I.B.College, Panipat, Haryana, INDIA.
Abstract
The aqueous fruit extract of Cucumis sativus L. was screened for free radical scavenging and analgesic activities. The extract was subjected to in vitro antioxidant studies at 250 and 500 μg/ml and analgesic study at the doses 250 and 500 mg/kg, respectively. The free radical scavenging was compared with ascorbic acid, BHA (Butylated hydroxyl anisole), whereas, the analgesic effect was compared with Diclofenac sodium (50 mg/kg). The C. sativus fruit extract showed maximum antioxidant and analgesic effect at 500 μg/ml and 500 mg/kg, respectively. The presence of flavonoids and tannins in the extract as evidenced by preliminary phytochemical screening suggests that these compounds might be responsible for free radical scavenging and analgesic effects.
Keywords: Analgesic; antioxidant; aqueous extract; Cucumis sativus
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