Pharmacognostical and Phytochemical Evaluation Leaves Ex tract of Garcinia daedalanthera Pierre

Abstract

Background: Garcinia daedalanthera is an Indonesian plant where com monly found in Sulawesi, Indonesia and spread out in the forest. Garcinia daedalanthera is one of Clusiaceae family that have been scientifically proven to provideantidiabetic and antioxidant activity but never been examined in pharmacognosy parameters. Pharmacognostical parameters of the leaves were studied with the aim of drawing the pharmacopoeial stan dards for this species.Methods: The present study was aimed to analysis the pharmacognosy of Garcinia daedalanthera including leaf morphology, microscopic characteristics, physicochemical parameters, phytochemical study, contaminant analysis and FTIR spectrum analysis.Results: The phy tochemical analysis revealed the presence of flavonoids, saponins, tannin, steroids and phenols.The moisture content was 2.35%, total ash 2.51%, acid insoluble ash 0.05%, total flavonoid and phenolic content were found to be 3.121% and 14.36% (w/w). The level of Arsenic (As), Cadmium (Cd) and lead (Pb) were found under the limit (0.357 ppm) and the extract of leaves Garcinia daedalanthera Pierre does not contain bacterial contamina tion.Conclusion: The data generated from this study would help in stan dardization for pharmacopoeial and prevent adulteration of leaves extract of Garcinia daedalanthera Pierre and the authentic plant material can be explored for its pharmacological.

Keywords: Standardization; Garcinia daedalanthera extract; FTIR; Macro microscopy study; preliminary screening; pharmacognosy study