Article · Volume 10, Issue 4 · pp. 146–149
Huperzinea: Pharmacological and Therapeutic Potential
Shagun Dubey Upadhyay1, Yusra Ahmad2, Rajesh Kumar Sharma3, Seema Kohli1
- 1Department of Pharmacy, Government Kalaniketan Polytechnic College, Jabalpur, Madhya Pradesh, INDIA.
- 2Faculty of Pharmacy, Uttarakhand Technical University, Dehradun, Uttarakhand, INDIA.
- 3College of Veterinary Science and Animal Husbandry, Nanaji Deshmukh University of Veterinary Science, Jabalpur, Madhya Pradesh, INDIA.
Abstract
Introduction: Huperzine A (HupA) is derived from a club moss (Huperzia serrata). It is a potent and reversible inhibitor of acetyl cholinesterase (AChE). Chemically, it is a sesquiterpene alkaloid. It has been used for the treatment of swelling, fever and blood disorders for centuries in China.Methodology: The literature available on Huperzine was thoroughly studied. It has shown much beneficial effect since ages. It is a established Nootropic agent and widely used in the treatment of Alzheimer’s disease. The plant has shown promising results in vivo and in vitro studies. Results and Conclusion: The present review highlights the pharmacological potential of Huperzine with its pharmacokinetic and pharmacokinetic studies and it’s rational for future prospective.
Keywords: Huperzine; Pharmacology; Neuroprotective agent; Pharmacokinetics
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