Article · Volume 13, Issue 1 · pp. 45
Rosella (Hibiscus sabdariffa L.) Tea may Protect against Alzheimer’s Disease
Ian E Cock1,2
- 1School of Environment and Science, Nathan Campus, Griffith University, Brisbane, Queensland, AUSTRALIA..
- 2Centre for Planetary Health and Food Security, Nathan Campus, Griffith University, Nathan, Brisbane, Queensland, AUSTRALIA..
Abstract
A recent study from a Pohang University, Korea group has reported that the hydroflavone gossypeptin, which is found in relative abundance in Hibiscus sabdariffa L., has therapeutic effects in a 5XFAD Alzheimer’s Disease (AD) mouse model.1 That mouse strain possesses human APP and PSEN1 transgenes, which are linked to familial AD and are known to enhance β-amyloid protein accumulation in brain cells. Mice treated with gossypeptin displayed significantly decreased cognitive impairment similar to those caused by AD.
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